Johnson JW - Search Results

1

Design, synthesis, and in vitro and in vivo characterization of new memantine analogs for Alzheimer's disease.

Turcu AL, Companys-Alemany J, Phillips MB, Patel DS, Griñán-Ferré C, Loza MI, Brea JM, Pérez B, Soto D, Sureda FX, Kurnikova MG, Johnson JW, Pallàs M, Vázquez S. Turcu AL, et al. Among authors: johnson jw. Eur J Med Chem. 2022 Jun 5;236:114354. doi: 10.1016/j.ejmech.2022.114354. Epub 2022 Apr 8. Eur J Med Chem. 2022. PMID: 35453065 Free PMC article.

2

Mg2+ imparts NMDA receptor subtype selectivity to the Alzheimer's drug memantine.

Kotermanski SE, Johnson JW. Kotermanski SE, et al. Among authors: johnson jw. J Neurosci. 2009 Mar 4;29(9):2774-9. doi: 10.1523/JNEUROSCI.3703-08.2009. J Neurosci. 2009. PMID: 19261873 Free PMC article.

3

Memantine binding to a superficial site on NMDA receptors contributes to partial trapping.

Kotermanski SE, Wood JT, Johnson JW. Kotermanski SE, et al. Among authors: johnson jw. J Physiol. 2009 Oct 1;587(Pt 19):4589-604. doi: 10.1113/jphysiol.2009.176297. Epub 2009 Aug 17. J Physiol. 2009. PMID: 19687120 Free PMC article.

4

Comparison of behavioral effects of the NMDA receptor channel blockers memantine and ketamine in rats.

Kotermanski SE, Johnson JW, Thiels E. Kotermanski SE, et al. Among authors: johnson jw. Pharmacol Biochem Behav. 2013 Aug;109:67-76. doi: 10.1016/j.pbb.2013.05.005. Epub 2013 May 8. Pharmacol Biochem Behav. 2013. PMID: 23665480 Free PMC article.

5

Recent insights into the mode of action of memantine and ketamine.

Johnson JW, Glasgow NG, Povysheva NV. Johnson JW, et al. Curr Opin Pharmacol. 2015 Feb;20:54-63. doi: 10.1016/j.coph.2014.11.006. Epub 2014 Dec 2. Curr Opin Pharmacol. 2015. PMID: 25462293 Free PMC article. Review.

6

All atom NMDA receptor transmembrane domain model development and simulations in lipid bilayers and water.

Mesbahi-Vasey S, Veras L, Yonkunas M, Johnson JW, Kurnikova MG. Mesbahi-Vasey S, et al. Among authors: johnson jw. PLoS One. 2017 Jun 5;12(6):e0177686. doi: 10.1371/journal.pone.0177686. eCollection 2017. PLoS One. 2017. PMID: 28582391 Free PMC article.

7

Pharmacological and Electrophysiological Characterization of Novel NMDA Receptor Antagonists.

Leiva R, Phillips MB, Turcu AL, Gratacòs-Batlle E, León-García L, Sureda FX, Soto D, Johnson JW, Vázquez S. Leiva R, et al. Among authors: johnson jw. ACS Chem Neurosci. 2018 Nov 21;9(11):2722-2730. doi: 10.1021/acschemneuro.8b00154. Epub 2018 Jun 1. ACS Chem Neurosci. 2018. PMID: 29767953 Free PMC article.

8

Effects of Mg²⁺ on recovery of NMDA receptors from inhibition by memantine and ketamine reveal properties of a second site.

Glasgow NG, Wilcox MR, Johnson JW. Glasgow NG, et al. Among authors: johnson jw. Neuropharmacology. 2018 Jul 15;137:344-358. doi: 10.1016/j.neuropharm.2018.05.017. Epub 2018 May 12. Neuropharmacology. 2018. PMID: 29793153 Free PMC article.

9

Synaptic zinc inhibition of NMDA receptors depends on the association of GluN2A with the zinc transporter ZnT1.

Krall RF, Moutal A, Phillips MB, Asraf H, Johnson JW, Khanna R, Hershfinkel M, Aizenman E, Tzounopoulos T. Krall RF, et al. Among authors: johnson jw. Sci Adv. 2020 Jul 3;6(27):eabb1515. doi: 10.1126/sciadv.abb1515. Print 2020 Jul. Sci Adv. 2020. PMID: 32937457 Free PMC article.

10

Interplay between Gating and Block of Ligand-Gated Ion Channels.

Phillips MB, Nigam A, Johnson JW. Phillips MB, et al. Among authors: johnson jw. Brain Sci. 2020 Dec 1;10(12):928. doi: 10.3390/brainsci10120928. Brain Sci. 2020. PMID: 33271923 Free PMC article. Review.

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