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Exploring the Use of Serum-Derived Small Extracellular Vesicles as Liquid Biopsy to Study the Induction of Hepatic Cytochromes P450 and Organic Anion Transporting Polypeptides.
Rodrigues AD, van Dyk M, Sorich MJ, Fahmy A, Useckaite Z, Newman LA, Kapetas AJ, Mounzer R, Wood LS, Johnson JG, Rowland A. Rodrigues AD, et al. Among authors: johnson jg. Clin Pharmacol Ther. 2021 Jul;110(1):248-258. doi: 10.1002/cpt.2244. Epub 2021 Apr 18. Clin Pharmacol Ther. 2021. PMID: 33792897
Identification of Appropriate Endogenous Biomarker for Risk Assessment of Multidrug and Toxin Extrusion Protein-Mediated Drug-Drug Interactions in Healthy Volunteers.
Miyake T, Kimoto E, Luo L, Mathialagan S, Horlbogen LM, Ramanathan R, Wood LS, Johnson JG, Le VH, Vourvahis M, Rodrigues AD, Muto C, Furihata K, Sugiyama Y, Kusuhara H. Miyake T, et al. Clin Pharmacol Ther. 2021 Feb;109(2):507-516. doi: 10.1002/cpt.2022. Epub 2020 Oct 9. Clin Pharmacol Ther. 2021. PMID: 32866300 Free PMC article. Clinical Trial.
In vitro studies with two human organic anion transporters: OAT2 and OAT7.
Mathialagan S, Costales C, Tylaska L, Kimoto E, Vildhede A, Johnson J, Johnson N, Sarashina T, Hashizume K, Isringhausen CD, Vermeer LMM, Wolff AR, Rodrigues AD. Mathialagan S, et al. Among authors: johnson n, johnson j. Xenobiotica. 2018 Oct;48(10):1037-1049. doi: 10.1080/00498254.2017.1384595. Epub 2017 Oct 13. Xenobiotica. 2018. PMID: 28945155
Dose-Dependent Inhibition of OATP1B by Rifampicin in Healthy Volunteers: Comprehensive Evaluation of Candidate Biomarkers and OATP1B Probe Drugs.
Mori D, Kimoto E, Rago B, Kondo Y, King-Ahmad A, Ramanathan R, Wood LS, Johnson JG, Le VH, Vourvahis M, David Rodrigues A, Muto C, Furihata K, Sugiyama Y, Kusuhara H. Mori D, et al. Clin Pharmacol Ther. 2020 Apr;107(4):1004-1013. doi: 10.1002/cpt.1695. Epub 2020 Jan 1. Clin Pharmacol Ther. 2020. PMID: 31628668 Free PMC article. Clinical Trial.
Modeling SARS-CoV-2: Comparative Pathology in Rhesus Macaque and Golden Syrian Hamster Models.
Choudhary S, Kanevsky I, Yildiz S, Sellers RS, Swanson KA, Franks T, Rathnasinghe R, Munoz-Moreno R, Jangra S, Gonzalez O, Meade P, Coskran T, Qian J, Lanz TA, Johnson JG, Tierney CA, Smith JD, Tompkins K, Illenberger A, Corts P, Ciolino T, Dormitzer PR, Dick EJ Jr, Shivanna V, Hall-Ursone S, Cole J, Kaushal D, Fontenot JA, Martinez-Romero C, McMahon M, Krammer F, Schotsaert M, García-Sastre A. Choudhary S, et al. Among authors: johnson jg. Toxicol Pathol. 2022 Apr;50(3):280-293. doi: 10.1177/01926233211072767. Epub 2022 Feb 5. Toxicol Pathol. 2022. PMID: 35128980 Free PMC article.
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