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Metabolomics: beyond biomarkers and towards mechanisms.
Johnson CH, Ivanisevic J, Siuzdak G. Johnson CH, et al. Nat Rev Mol Cell Biol. 2016 Jul;17(7):451-9. doi: 10.1038/nrm.2016.25. Epub 2016 Mar 16. Nat Rev Mol Cell Biol. 2016. PMID: 26979502 Free PMC article.
Systems biology guided by XCMS Online metabolomics.
Huan T, Forsberg EM, Rinehart D, Johnson CH, Ivanisevic J, Benton HP, Fang M, Aisporna A, Hilmers B, Poole FL, Thorgersen MP, Adams MWW, Krantz G, Fields MW, Robbins PD, Niedernhofer LJ, Ideker T, Majumder EL, Wall JD, Rattray NJW, Goodacre R, Lairson LL, Siuzdak G. Huan T, et al. Among authors: johnson ch. Nat Methods. 2017 Apr 27;14(5):461-462. doi: 10.1038/nmeth.4260. Nat Methods. 2017. PMID: 28448069 Free PMC article. No abstract available.
Thermal Degradation of Small Molecules: A Global Metabolomic Investigation.
Fang M, Ivanisevic J, Benton HP, Johnson CH, Patti GJ, Hoang LT, Uritboonthai W, Kurczy ME, Siuzdak G. Fang M, et al. Among authors: johnson ch. Anal Chem. 2015 Nov 3;87(21):10935-41. doi: 10.1021/acs.analchem.5b03003. Epub 2015 Oct 14. Anal Chem. 2015. PMID: 26434689 Free PMC article.
Global metabolomics reveals metabolic dysregulation in ischemic retinopathy.
Paris LP, Johnson CH, Aguilar E, Usui Y, Cho K, Hoang LT, Feitelberg D, Benton HP, Westenskow PD, Kurihara T, Trombley J, Tsubota K, Ueda S, Wakabayashi Y, Patti GJ, Ivanisevic J, Siuzdak G, Friedlander M. Paris LP, et al. Among authors: johnson ch. Metabolomics. 2016;12:15. doi: 10.1007/s11306-015-0877-5. Epub 2015 Nov 18. Metabolomics. 2016. PMID: 26617478 Free PMC article.
Exposome-Scale Investigations Guided by Global Metabolomics, Pathway Analysis, and Cognitive Computing.
Warth B, Spangler S, Fang M, Johnson CH, Forsberg EM, Granados A, Martin RL, Domingo-Almenara X, Huan T, Rinehart D, Montenegro-Burke JR, Hilmers B, Aisporna A, Hoang LT, Uritboonthai W, Benton HP, Richardson SD, Williams AJ, Siuzdak G. Warth B, et al. Among authors: johnson ch. Anal Chem. 2017 Nov 7;89(21):11505-11513. doi: 10.1021/acs.analchem.7b02759. Epub 2017 Oct 9. Anal Chem. 2017. PMID: 28945073
Metabolite and Microbiome Interplay in Cancer Immunotherapy.
Johnson CH, Spilker ME, Goetz L, Peterson SN, Siuzdak G. Johnson CH, et al. Cancer Res. 2016 Nov 1;76(21):6146-6152. doi: 10.1158/0008-5472.CAN-16-0309. Epub 2016 Oct 11. Cancer Res. 2016. PMID: 27729325 Free PMC article. Review.
Spontaneous DNA damage to the nuclear genome promotes senescence, redox imbalance and aging.
Robinson AR, Yousefzadeh MJ, Rozgaja TA, Wang J, Li X, Tilstra JS, Feldman CH, Gregg SQ, Johnson CH, Skoda EM, Frantz MC, Bell-Temin H, Pope-Varsalona H, Gurkar AU, Nasto LA, Robinson RAS, Fuhrmann-Stroissnigg H, Czerwinska J, McGowan SJ, Cantu-Medellin N, Harris JB, Maniar S, Ross MA, Trussoni CE, LaRusso NF, Cifuentes-Pagano E, Pagano PJ, Tudek B, Vo NV, Rigatti LH, Opresko PL, Stolz DB, Watkins SC, Burd CE, Croix CMS, Siuzdak G, Yates NA, Robbins PD, Wang Y, Wipf P, Kelley EE, Niedernhofer LJ. Robinson AR, et al. Among authors: johnson ch. Redox Biol. 2018 Jul;17:259-273. doi: 10.1016/j.redox.2018.04.007. Epub 2018 Apr 13. Redox Biol. 2018. PMID: 29747066 Free PMC article.
Challenges and opportunities of metabolomics.
Johnson CH, Gonzalez FJ. Johnson CH, et al. J Cell Physiol. 2012 Aug;227(8):2975-81. doi: 10.1002/jcp.24002. J Cell Physiol. 2012. PMID: 22034100 Free PMC article. Review.
443 results