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Therapeutic efficacy of antimalarial drugs targeting DosRS signaling in Mycobacterium abscessus.
Belardinelli JM, Verma D, Li W, Avanzi C, Wiersma CJ, Williams JT, Johnson BK, Zimmerman M, Whittel N, Angala B, Wang H, Jones V, Dartois V, de Moura VCN, Gonzalez-Juarrero M, Pearce C, Schenkel AR, Malcolm KC, Nick JA, Charman SA, Wells TNC, Podell BK, Vennerstrom JL, Ordway DJ, Abramovitch RB, Jackson M. Belardinelli JM, et al. Among authors: johnson bk. Sci Transl Med. 2022 Feb 23;14(633):eabj3860. doi: 10.1126/scitranslmed.abj3860. Epub 2022 Feb 23. Sci Transl Med. 2022. PMID: 35196022 Free PMC article.
Inhibitors of Mycobacterium tuberculosis DosRST signaling and persistence.
Zheng H, Colvin CJ, Johnson BK, Kirchhoff PD, Wilson M, Jorgensen-Muga K, Larsen SD, Abramovitch RB. Zheng H, et al. Among authors: johnson bk. Nat Chem Biol. 2017 Feb;13(2):218-225. doi: 10.1038/nchembio.2259. Epub 2016 Dec 19. Nat Chem Biol. 2017. PMID: 27992879
Small Molecules That Sabotage Bacterial Virulence.
Johnson BK, Abramovitch RB. Johnson BK, et al. Trends Pharmacol Sci. 2017 Apr;38(4):339-362. doi: 10.1016/j.tips.2017.01.004. Epub 2017 Feb 14. Trends Pharmacol Sci. 2017. PMID: 28209403 Free PMC article. Review.
2-aminoimidazoles potentiate ß-lactam antimicrobial activity against Mycobacterium tuberculosis by reducing ß-lactamase secretion and increasing cell envelope permeability.
Jeon AB, Obregón-Henao A, Ackart DF, Podell BK, Belardinelli JM, Jackson M, Nguyen TV, Blackledge MS, Melander RJ, Melander C, Johnson BK, Abramovitch RB, Basaraba RJ. Jeon AB, et al. Among authors: johnson bk. PLoS One. 2017 Jul 27;12(7):e0180925. doi: 10.1371/journal.pone.0180925. eCollection 2017. PLoS One. 2017. PMID: 28749949 Free PMC article.
161 results