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Novel monoclonal antibody specific for the de2-7 epidermal growth factor receptor (EGFR) that also recognizes the EGFR expressed in cells containing amplification of the EGFR gene.
Johns TG, Stockert E, Ritter G, Jungbluth AA, Huang HJ, Cavenee WK, Smyth FE, Hall CM, Watson N, Nice EC, Gullick WJ, Old LJ, Burgess AW, Scott AM. Johns TG, et al. Int J Cancer. 2002 Mar 20;98(3):398-408. doi: 10.1002/ijc.10189. Int J Cancer. 2002. PMID: 11920591 Free article.
Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor.
Johns TG, Adams TE, Cochran JR, Hall NE, Hoyne PA, Olsen MJ, Kim YS, Rothacker J, Nice EC, Walker F, Ritter G, Jungbluth AA, Old LJ, Ward CW, Burgess AW, Wittrup KD, Scott AM. Johns TG, et al. J Biol Chem. 2004 Jul 16;279(29):30375-84. doi: 10.1074/jbc.M401218200. Epub 2004 Apr 9. J Biol Chem. 2004. PMID: 15075331 Free article.
Engineering and characterisation of chimeric monoclonal antibody 806 (ch806) for targeted immunotherapy of tumours expressing de2-7 EGFR or amplified EGFR.
Panousis C, Rayzman VM, Johns TG, Renner C, Liu Z, Cartwright G, Lee FT, Wang D, Gan H, Cao D, Kypridis A, Smyth FE, Brechbiel MW, Burgess AW, Old LJ, Scott AM. Panousis C, et al. Among authors: johns tg. Br J Cancer. 2005 Mar 28;92(6):1069-77. doi: 10.1038/sj.bjc.6602470. Br J Cancer. 2005. PMID: 15770208 Free PMC article.
115 results