Johns TG - Search Results

1

Activation of ERBB4 in Glioblastoma Can Contribute to Increased Tumorigenicity and Influence Therapeutic Response.

Donoghue JF, Kerr LT, Alexander NW, Greenall SA, Longano AB, Gottardo NG, Wang R, Tabar V, Adams TE, Mischel PS, Johns TG. Donoghue JF, et al. Among authors: johns tg. Cancers (Basel). 2018 Jul 25;10(8):243. doi: 10.3390/cancers10080243. Cancers (Basel). 2018. PMID: 30044378 Free PMC article.

2

CR1/CR2 interactions modulate the functions of the cell surface epidermal growth factor receptor.

Walker F, Orchard SG, Jorissen RN, Hall NE, Zhang HH, Hoyne PA, Adams TE, Johns TG, Ward C, Garrett TP, Zhu HJ, Nerrie M, Scott AM, Nice EC, Burgess AW. Walker F, et al. Among authors: johns tg. J Biol Chem. 2004 May 21;279(21):22387-98. doi: 10.1074/jbc.M401244200. Epub 2004 Mar 11. J Biol Chem. 2004. PMID: 15016810 Free article.

3

Identification of the epitope for the epidermal growth factor receptor-specific monoclonal antibody 806 reveals that it preferentially recognizes an untethered form of the receptor.

Johns TG, Adams TE, Cochran JR, Hall NE, Hoyne PA, Olsen MJ, Kim YS, Rothacker J, Nice EC, Walker F, Ritter G, Jungbluth AA, Old LJ, Ward CW, Burgess AW, Wittrup KD, Scott AM. Johns TG, et al. J Biol Chem. 2004 Jul 16;279(29):30375-84. doi: 10.1074/jbc.M401218200. Epub 2004 Apr 9. J Biol Chem. 2004. PMID: 15075331 Free article.

4

A truncated soluble epidermal growth factor receptor-Fc fusion ligand trap displays anti-tumour activity in vivo.

Adams TE, Koziolek EJ, Hoyne PH, Bentley JD, Lu L, Lovrecz G, Ward CW, Lee FT, Scott AM, Nash AD, Rothacker J, Nice EC, Burgess AW, Johns TG. Adams TE, et al. Among authors: johns tg. Growth Factors. 2009 Jun;27(3):141-54. doi: 10.1080/08977190902843565. Growth Factors. 2009. PMID: 19333814

5

Fyn and SRC are effectors of oncogenic epidermal growth factor receptor signaling in glioblastoma patients.

Lu KV, Zhu S, Cvrljevic A, Huang TT, Sarkaria S, Ahkavan D, Dang J, Dinca EB, Plaisier SB, Oderberg I, Lee Y, Chen Z, Caldwell JS, Xie Y, Loo JA, Seligson D, Chakravari A, Lee FY, Weinmann R, Cloughesy TF, Nelson SF, Bergers G, Graeber T, Furnari FB, James CD, Cavenee WK, Johns TG, Mischel PS. Lu KV, et al. Among authors: johns tg. Cancer Res. 2009 Sep 1;69(17):6889-98. doi: 10.1158/0008-5472.CAN-09-0347. Epub 2009 Aug 18. Cancer Res. 2009. PMID: 19690143 Free PMC article.

6

Activation of Src induces mitochondrial localisation of de2-7EGFR (EGFRvIII) in glioma cells: implications for glucose metabolism.

Cvrljevic AN, Akhavan D, Wu M, Martinello P, Furnari FB, Johnston AJ, Guo D, Pike L, Cavenee WK, Scott AM, Mischel PS, Hoogenraad NJ, Johns TG. Cvrljevic AN, et al. Among authors: johns tg. J Cell Sci. 2011 Sep 1;124(Pt 17):2938-50. doi: 10.1242/jcs.083295. J Cell Sci. 2011. PMID: 21878501 Free PMC article.

7

A simple guide screw method for intracranial xenograft studies in mice.

Donoghue JF, Bogler O, Johns TG. Donoghue JF, et al. Among authors: johns tg. J Vis Exp. 2011 Sep 26;(55):3157. doi: 10.3791/3157. J Vis Exp. 2011. PMID: 21968439 Free PMC article.

8

Non-agonistic bivalent antibodies that promote c-MET degradation and inhibit tumor growth and others specific for tumor related c-MET.

Greenall SA, Gherardi E, Liu Z, Donoghue JF, Vitali AA, Li Q, Murphy R, Iamele L, Scott AM, Johns TG. Greenall SA, et al. Among authors: johns tg. PLoS One. 2012;7(4):e34658. doi: 10.1371/journal.pone.0034658. Epub 2012 Apr 12. PLoS One. 2012. PMID: 22511956 Free PMC article.

9

A high-affinity ErbB4Fc fusion protein is a potent antagonist of heregulin-mediated receptor activation.

Koziolek EJ, Donoghue JF, Bentley JD, Lovrecz G, Dolezal O, Ward CW, Rothacker J, Nice EC, Burgess AW, Hafner M, Johns TG, Adams TE. Koziolek EJ, et al. Among authors: johns tg. Growth Factors. 2012 Oct;30(5):310-9. doi: 10.3109/08977194.2012.709516. Epub 2012 Aug 2. Growth Factors. 2012. PMID: 22856597

10

The regulation of mitochondrial DNA copy number in glioblastoma cells.

Dickinson A, Yeung KY, Donoghue J, Baker MJ, Kelly RD, McKenzie M, Johns TG, St John JC. Dickinson A, et al. Among authors: johns tg. Cell Death Differ. 2013 Dec;20(12):1644-53. doi: 10.1038/cdd.2013.115. Epub 2013 Aug 30. Cell Death Differ. 2013. PMID: 23995230 Free PMC article.

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