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Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells.
Chauss D, Freiwald T, McGregor R, Yan B, Wang L, Nova-Lamperti E, Kumar D, Zhang Z, Teague H, West EE, Vannella KM, Ramos-Benitez MJ, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz DM, Portilla D, Chertow DS, John S, Lavender P, Kemper C, Lombardi G, Mehta NN, Cooper N, Lionakis MS, Laurence A, Kazemian M, Afzali B. Chauss D, et al. Among authors: john s. Nat Immunol. 2022 Jan;23(1):62-74. doi: 10.1038/s41590-021-01080-3. Epub 2021 Nov 11. Nat Immunol. 2022. PMID: 34764490 Free PMC article.
IL-2 regulates expression of C-MAF in human CD4 T cells.
Rani A, Afzali B, Kelly A, Tewolde-Berhan L, Hackett M, Kanhere AS, Pedroza-Pacheco I, Bowen H, Jurcevic S, Jenner RG, Cousins DJ, Ragheb JA, Lavender P, John S. Rani A, et al. Among authors: john s. J Immunol. 2011 Oct 1;187(7):3721-9. doi: 10.4049/jimmunol.1002354. Epub 2011 Aug 29. J Immunol. 2011. PMID: 21876034 Free PMC article.
CD161 expression characterizes a subpopulation of human regulatory T cells that produces IL-17 in a STAT3-dependent manner.
Afzali B, Mitchell PJ, Edozie FC, Povoleri GA, Dowson SE, Demandt L, Walter G, Canavan JB, Scotta C, Menon B, Chana PS, Khamri W, Kordasti SY, Heck S, Grimbacher B, Tree T, Cope AP, Taams LS, Lechler RI, John S, Lombardi G. Afzali B, et al. Among authors: john s. Eur J Immunol. 2013 Aug;43(8):2043-54. doi: 10.1002/eji.201243296. Epub 2013 Jul 3. Eur J Immunol. 2013. PMID: 23677517 Free PMC article.
Reduced TCR Signaling Contributes to Impaired Th17 Responses in Tolerant Kidney Transplant Recipients.
Nova-Lamperti E, Romano M, Christakoudi S, Runglall M, McGregor R, Mobillo P, Kamra Y, Tsui TL, Norris S, John S, Boardman DA, Lechler RI, Lombardi G, Hernandez-Fuentes MP; www.GAMBITstudy.co.uk. Nova-Lamperti E, et al. Among authors: john s. Transplantation. 2018 Jan;102(1):e10-e17. doi: 10.1097/TP.0000000000001920. Transplantation. 2018. PMID: 28902773 Free PMC article.
An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19.
McGregor R, Chauss D, Freiwald T, Yan B, Wang L, Nova-Lamperti E, Zhang Z, Teague H, West EE, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz D, Portilla D, John S, Lavender P, Lionakis MS, Mehta NN, Kemper C, Cooper N, Lombardi G, Laurence A, Kazemian M, Afzali B. McGregor R, et al. Among authors: john s. bioRxiv [Preprint]. 2020 Jul 19:2020.07.18.210161. doi: 10.1101/2020.07.18.210161. bioRxiv. 2020. PMID: 32743590 Free PMC article. Preprint.
2,779 results