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Page 1
Pharmacological inhibition of TBK1/IKKε blunts immunopathology in a murine model of SARS-CoV-2 infection.
Ullah TR, Johansen MD, Balka KR, Ambrose RL, Gearing LJ, Roest J, Vivian JP, Sapkota S, Jayasekara WSN, Wenholz DS, Aldilla VR, Zeng J, Miemczyk S, Nguyen DH, Hansbro NG, Venkatraman R, Kang JH, Pang ES, Thomas BJ, Alharbi AS, Rezwan R, O'Keeffe M, Donald WA, Ellyard JI, Wong W, Kumar N, Kile BT, Vinuesa CG, Kelly GE, Laczka OF, Hansbro PM, De Nardo D, Gantier MP. Ullah TR, et al. Among authors: johansen md. Nat Commun. 2023 Sep 18;14(1):5666. doi: 10.1038/s41467-023-41381-9. Nat Commun. 2023. PMID: 37723181 Free PMC article.
Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon.
Ryan TAJ, Hooftman A, Rehill AM, Johansen MD, Brien ECO, Toller-Kawahisa JE, Wilk MM, Day EA, Weiss HJ, Sarvari P, Vozza EG, Schramm F, Peace CG, Zotta A, Miemczyk S, Nalkurthi C, Hansbro NG, McManus G, O'Doherty L, Gargan S, Long A, Dunne J, Cheallaigh CN, Conlon N, Carty M, Fallon PG, Mills KHG, Creagh EM, Donnell JSO, Hertzog PJ, Hansbro PM, McLoughlin RM, Wygrecka M, Preston RJS, Zasłona Z, O'Neill LAJ. Ryan TAJ, et al. Among authors: johansen md. Nat Commun. 2023 Jun 14;14(1):3513. doi: 10.1038/s41467-023-39174-1. Nat Commun. 2023. PMID: 37316487 Free PMC article.
Increased SARS-CoV-2 Infection, Protease, and Inflammatory Responses in Chronic Obstructive Pulmonary Disease Primary Bronchial Epithelial Cells Defined with Single-Cell RNA Sequencing.
Johansen MD, Mahbub RM, Idrees S, Nguyen DH, Miemczyk S, Pathinayake P, Nichol K, Hansbro NG, Gearing LJ, Hertzog PJ, Gallego-Ortega D, Britton WJ, Saunders BM, Wark PA, Faiz A, Hansbro PM. Johansen MD, et al. Am J Respir Crit Care Med. 2022 Sep 15;206(6):712-729. doi: 10.1164/rccm.202108-1901OC. Am J Respir Crit Care Med. 2022. PMID: 35549656 Free PMC article.
Broadly neutralizing SARS-CoV-2 antibodies through epitope-based selection from convalescent patients.
Rouet R, Henry JY, Johansen MD, Sobti M, Balachandran H, Langley DB, Walker GJ, Lenthall H, Jackson J, Ubiparipovic S, Mazigi O, Schofield P, Burnett DL, Brown SHJ, Martinello M, Hudson B, Gilroy N, Post JJ, Kelleher A, Jäck HM, Goodnow CC, Turville SG, Rawlinson WD, Bull RA, Stewart AG, Hansbro PM, Christ D. Rouet R, et al. Among authors: johansen md. Nat Commun. 2023 Feb 8;14(1):687. doi: 10.1038/s41467-023-36295-5. Nat Commun. 2023. PMID: 36755042 Free PMC article.
Publisher Correction: Dimethyl fumarate and 4-octyl itaconate are anticoagulants that suppress Tissue Factor in macrophages via inhibition of Type I Interferon.
Ryan TAJ, Hooftman A, Rehill AM, Johansen MD, O' Brien EC, Toller-Kawahisa JE, Wilk MM, Day EA, Weiss HJ, Sarvari P, Vozza EG, Schramm F, Peace CG, Zotta A, Miemczyk S, Nalkurthi C, Hansbro NG, McManus G, O'Doherty L, Gargan S, Long A, Dunne J, Cheallaigh CN, Conlon N, Carty M, Fallon PG, Mills KHG, Creagh EM, O' Donnell JS, Hertzog PJ, Hansbro PM, McLoughlin RM, Wygrecka M, Preston RJS, Zasłona Z, O'Neill LAJ. Ryan TAJ, et al. Among authors: johansen md. Nat Commun. 2023 Jul 20;14(1):4374. doi: 10.1038/s41467-023-40034-1. Nat Commun. 2023. PMID: 37474527 Free PMC article. No abstract available.
Animal and translational models of SARS-CoV-2 infection and COVID-19.
Johansen MD, Irving A, Montagutelli X, Tate MD, Rudloff I, Nold MF, Hansbro NG, Kim RY, Donovan C, Liu G, Faiz A, Short KR, Lyons JG, McCaughan GW, Gorrell MD, Cole A, Moreno C, Couteur D, Hesselson D, Triccas J, Neely GG, Gamble JR, Simpson SJ, Saunders BM, Oliver BG, Britton WJ, Wark PA, Nold-Petry CA, Hansbro PM. Johansen MD, et al. Mucosal Immunol. 2020 Nov;13(6):877-891. doi: 10.1038/s41385-020-00340-z. Epub 2020 Aug 20. Mucosal Immunol. 2020. PMID: 32820248 Free PMC article. Review.
A single dose, BCG-adjuvanted COVID-19 vaccine provides sterilising immunity against SARS-CoV-2 infection.
Counoupas C, Johansen MD, Stella AO, Nguyen DH, Ferguson AL, Aggarwal A, Bhattacharyya ND, Grey A, Hutchings O, Patel K, Siddiquee R, Stewart EL, Feng CG, Hansbro NG, Palendira U, Steain MC, Saunders BM, Low JKK, Mackay JP, Kelleher AD, Britton WJ, Turville SG, Hansbro PM, Triccas JA. Counoupas C, et al. Among authors: johansen md. NPJ Vaccines. 2021 Nov 30;6(1):143. doi: 10.1038/s41541-021-00406-4. NPJ Vaccines. 2021. PMID: 34848711 Free PMC article.
The complex interplay between endoplasmic reticulum stress and the NLRP3 inflammasome: a potential therapeutic target for inflammatory disorders.
Chong WC, Shastri MD, Peterson GM, Patel RP, Pathinayake PS, Dua K, Hansbro NG, Hsu AC, Wark PA, Shukla SD, Johansen MD, Schroder K, Hansbro PM. Chong WC, et al. Among authors: johansen md. Clin Transl Immunology. 2021 Feb 11;10(2):e1247. doi: 10.1002/cti2.1247. eCollection 2021. Clin Transl Immunology. 2021. PMID: 33614031 Free PMC article. Review.
Clinical features and mechanistic insights into drug repurposing for combating COVID-19.
Asrani P, Tiwari K, Eapen MS, McAlinden KD, Haug G, Johansen MD, Hansbro PM, Flanagan KL, Hassan MI, Sohal SS. Asrani P, et al. Among authors: johansen md. Int J Biochem Cell Biol. 2022 Jan;142:106114. doi: 10.1016/j.biocel.2021.106114. Epub 2021 Nov 5. Int J Biochem Cell Biol. 2022. PMID: 34748991 Free PMC article. Review.
69 results