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Azithromycin blocks quorum sensing and alginate polymer formation and increases the sensitivity to serum and stationary-growth-phase killing of Pseudomonas aeruginosa and attenuates chronic P. aeruginosa lung infection in Cftr(-/-) mice.
Hoffmann N, Lee B, Hentzer M, Rasmussen TB, Song Z, Johansen HK, Givskov M, Høiby N. Hoffmann N, et al. Among authors: johansen hk. Antimicrob Agents Chemother. 2007 Oct;51(10):3677-87. doi: 10.1128/AAC.01011-06. Epub 2007 Jul 9. Antimicrob Agents Chemother. 2007. PMID: 17620382 Free PMC article.
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