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Protein and lipid binding parameters in rainbow trout (Oncorhynchus mykiss) blood and liver fractions to extrapolate from an in vitro metabolic degradation assay to in vivo bioaccumulation potential of hydrophobic organic chemicals.
Escher BI, Cowan-Ellsberry CE, Dyer S, Embry MR, Erhardt S, Halder M, Kwon JH, Johanning K, Oosterwijk MT, Rutishauser S, Segner H, Nichols J. Escher BI, et al. Chem Res Toxicol. 2011 Jul 18;24(7):1134-43. doi: 10.1021/tx200114y. Epub 2011 Jun 8. Chem Res Toxicol. 2011. PMID: 21604782
Assessment of metabolic stability using the rainbow trout (Oncorhynchus mykiss) liver S9 fraction.
Johanning K, Hancock G, Escher B, Adekola A, Bernhard MJ, Cowan-Ellsberry C, Domoradzki J, Dyer S, Eickhoff C, Embry M, Erhardt S, Fitzsimmons P, Halder M, Hill J, Holden D, Johnson R, Rutishauser S, Segner H, Schultz I, Nichols J. Johanning K, et al. Curr Protoc Toxicol. 2012 Aug;Chapter 14:Unit 14.10.1-28. doi: 10.1002/0471140856.tx1410s53. Curr Protoc Toxicol. 2012. PMID: 22896006
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