Joel P Mackay - Search Results

Year	Number of Results
2001	1
2002	12
2003	6
2004	8
2005	11
2006	7
2007	9
2008	11
2009	7
2010	6
2011	15
2012	11
2013	9
2014	10
2015	4
2016	10
2017	7
2018	5
2019	7
2020	13
2021	8
2022	9
2023	12
2024	3

1

ZNF827 is a single-stranded DNA binding protein that regulates the ATR-CHK1 DNA damage response pathway.

Yang SF, Nelson CB, Wells JK, Fernando M, Lu R, Allen JAM, Malloy L, Lamm N, Murphy VJ, Mackay JP, Deans AJ, Cesare AJ, Sobinoff AP, Pickett HA. Yang SF, et al. Among authors: mackay jp. Nat Commun. 2024 Mar 12;15(1):2210. doi: 10.1038/s41467-024-46578-0. Nat Commun. 2024. PMID: 38472229 Free PMC article.

2

Base editing of key residues in the BCL11A-XL-specific zinc finger domains derepresses fetal globin expression.

Rajendiran V, Devaraju N, Haddad M, Ravi NS, Panigrahi L, Paul J, Gopalakrishnan C, Wyman S, Ariudainambi K, Mahalingam G, Periyasami Y, Prasad K, George A, Sukumaran D, Gopinathan S, Pai AA, Nakamura Y, Balasubramanian P, Ramalingam R, Thangavel S, Velayudhan SR, Corn JE, Mackay JP, Marepally S, Srivastava A, Crossley M, Mohankumar KM. Rajendiran V, et al. Among authors: mackay jp. Mol Ther. 2024 Mar 6;32(3):663-677. doi: 10.1016/j.ymthe.2024.01.023. Epub 2024 Jan 24. Mol Ther. 2024. PMID: 38273654 Free article.

3

Discovery of High Affinity Cyclic Peptide Ligands for Human ACE2 with SARS-CoV-2 Entry Inhibitory Activity.

Bedding MJ, Franck C, Johansen-Leete J, Aggarwal A, Maxwell JWC, Patel K, Hawkins PME, Low JKK, Siddiquee R, Sani HM, Ford DJ, Turville S, Mackay JP, Passioura T, Christie M, Payne RJ. Bedding MJ, et al. Among authors: mackay jp. ACS Chem Biol. 2024 Jan 19;19(1):141-152. doi: 10.1021/acschembio.3c00568. Epub 2023 Dec 12. ACS Chem Biol. 2024. PMID: 38085789

4

mRNA display reveals a class of high-affinity bromodomain-binding motifs that are not found in the human proteome.

Low JKK, Patel K, Jones N, Solomon P, Norman A, Maxwell JWC, Pachl P, Matthews JM, Payne RJ, Passioura T, Suga H, Walport LJ, Mackay JP. Low JKK, et al. Among authors: mackay jp. J Biol Chem. 2023 Dec;299(12):105482. doi: 10.1016/j.jbc.2023.105482. Epub 2023 Nov 20. J Biol Chem. 2023. PMID: 37992806 Free PMC article.

5

Dynamin 1xA interacts with Endophilin A1 via its spliced long C-terminus for ultrafast endocytosis.

Imoto Y, Xue J, Luo L, Raychaudhuri S, Itoh K, Ma Y, Craft GE, Kwan AH, Mackay JP, Ha T, Watanabe S, Robinson PJ. Imoto Y, et al. Among authors: mackay jp. bioRxiv [Preprint]. 2023 Sep 24:2023.09.21.558797. doi: 10.1101/2023.09.21.558797. bioRxiv. 2023. PMID: 37790502 Free PMC article. Preprint.

6

Discovery and characterization of cyclic peptides selective for the C-terminal bromodomains of BET family proteins.

Franck C, Patel K, Walport LJ, Christie M, Norman A, Passioura T, Suga H, Payne RJ, Mackay JP. Franck C, et al. Among authors: mackay jp. Structure. 2023 Aug 3;31(8):912-923.e4. doi: 10.1016/j.str.2023.05.009. Epub 2023 Jun 2. Structure. 2023. PMID: 37269828

7

DUF2285 is a novel helix-turn-helix domain variant that orchestrates both activation and antiactivation of conjugative element transfer in proteobacteria.

Jowsey WJ, Morris CRP, Hall DA, Sullivan JT, Fagerlund RD, Eto KY, Solomon PD, Mackay JP, Bond CS, Ramsay JP, Ronson CW. Jowsey WJ, et al. Among authors: mackay jp. Nucleic Acids Res. 2023 Jul 21;51(13):6841-6856. doi: 10.1093/nar/gkad457. Nucleic Acids Res. 2023. PMID: 37246713 Free PMC article.

8

De novo variants in GATAD2A in individuals with a neurodevelopmental disorder: GATAD2A-related neurodevelopmental disorder.

Werren EA, Guxholli A, Jones N, Wagner M, Hannibal I, Granadillo JL, Tyndall AV, Moccia A, Kuehl R, Levandoski KM, Day-Salvatore DL, Wheeler M; University of Washington Center for Mendelian Genomics; Chong JX, Bamshad MJ, Innes AM, Pierson TM, Mackay JP, Bielas SL, Martin DM. Werren EA, et al. Among authors: mackay jp. HGG Adv. 2023 Apr 20;4(3):100198. doi: 10.1016/j.xhgg.2023.100198. eCollection 2023 Jul 13. HGG Adv. 2023. PMID: 37181331 Free PMC article.

9

Cross-linking mass spectrometry discovers, evaluates, and corroborates structures and protein-protein interactions in the human cell.

Bartolec TK, Vázquez-Campos X, Norman A, Luong C, Johnson M, Payne RJ, Wilkins MR, Mackay JP, Low JKK. Bartolec TK, et al. Among authors: mackay jp. Proc Natl Acad Sci U S A. 2023 Apr 25;120(17):e2219418120. doi: 10.1073/pnas.2219418120. Epub 2023 Apr 18. Proc Natl Acad Sci U S A. 2023. PMID: 37071682 Free PMC article.

10

Rapid Elaboration of Fragments into Leads Applied to Bromodomain-3 Extra-Terminal Domain.

Adams LA, Wilkinson-White LE, Gunzburg MJ, Headey SJ, Mohanty B, Scanlon MJ, Capuano B, Mackay JP, Doak BC. Adams LA, et al. Among authors: mackay jp. J Med Chem. 2023 Apr 27;66(8):5859-5872. doi: 10.1021/acs.jmedchem.3c00137. Epub 2023 Apr 18. J Med Chem. 2023. PMID: 37071570

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