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A Randomized Controlled Clinical Trial of Nasal Immunization with Live Virulence Attenuated Streptococcus pneumoniae Strains Using Human Infection Challenge.
Hill H, Mitsi E, Nikolaou E, Blizard A, Pojar S, Howard A, Hyder-Wright A, Devin J, Reiné J, Robinson R, Solórzano C, Jochems SP, Kenny-Nyazika T, Ramos-Sevillano E, Weight CM, Myerscough C, McLenaghan D, Morton B, Gibbons E, Farrar M, Randles V, Burhan H, Chen T, Shandling AD, Campo JJ, Heyderman RS, Gordon SB, Brown JS, Collins AM, Ferreira DM. Hill H, et al. Among authors: jochems sp. Am J Respir Crit Care Med. 2023 Oct 15;208(8):868-878. doi: 10.1164/rccm.202302-0222OC. Am J Respir Crit Care Med. 2023. PMID: 37556679 Clinical Trial.
Characterization of T cell responses to co-administered hookworm vaccine candidates Na-GST-1 and Na-APR-1 in healthy adults in Gabon.
Mouwenda YD, Betouke Ongwe ME, Sonnet F, Stam KA, Labuda LA, De Vries S, Grobusch MP, Zinsou FJ, Honkpehedji YJ, Dejon Agobe JC, Diemert DJ, van Leeuwen R, Bottazzi ME, Hotez PJ, Kremsner PG, Bethony JM, Jochems SP, Adegnika AA, Massinga Loembe M, Yazdanbakhsh M. Mouwenda YD, et al. Among authors: jochems sp. PLoS Negl Trop Dis. 2021 Oct 1;15(10):e0009732. doi: 10.1371/journal.pntd.0009732. eCollection 2021 Oct. PLoS Negl Trop Dis. 2021. PMID: 34597297 Free PMC article. Clinical Trial.
Systemic DPP4 activity is reduced during primary HIV-1 infection and is associated with intestinal RORC+ CD4+ cell levels: a surrogate marker candidate of HIV-induced intestinal damage.
Ploquin MJ, Casrouge A, Madec Y, Noël N, Jacquelin B, Huot N, Duffy D, Jochems SP, Micci L, Lécuroux C, Boufassa F, Booiman T, Garcia-Tellez T, Ghislain M, Grand RL, Lambotte O, Kootstra N, Meyer L, Goujard C, Paiardini M, Albert ML, Müller-Trutwin M. Ploquin MJ, et al. Among authors: jochems sp. J Int AIDS Soc. 2018 Jul;21(7):e25144. doi: 10.1002/jia2.25144. J Int AIDS Soc. 2018. PMID: 29987877 Free PMC article.
Plasmacytoid Dendritic Cell Infection and Sensing Capacity during Pathogenic and Nonpathogenic Simian Immunodeficiency Virus Infection.
Jochems SP, Jacquelin B, Chauveau L, Huot N, Petitjean G, Lepelley A, Liovat AS, Ploquin MJ, Cartwright EK, Bosinger SE, Silvestri G, Barré-Sinoussi F, Lebon P, Schwartz O, Müller-Trutwin MC. Jochems SP, et al. J Virol. 2015 Jul;89(13):6918-27. doi: 10.1128/JVI.00332-15. Epub 2015 Apr 22. J Virol. 2015. PMID: 25903334 Free PMC article.
Novel Analysis of Immune Cells from Nasal Microbiopsy Demonstrates Reliable, Reproducible Data for Immune Populations, and Superior Cytokine Detection Compared to Nasal Wash.
Jochems SP, Piddock K, Rylance J, Adler H, Carniel BF, Collins A, Gritzfeld JF, Hancock C, Hill H, Reiné J, Seddon A, Solórzano C, Sunny S, Trimble A, Wright AD, Zaidi S, Gordon SB, Ferreira DM. Jochems SP, et al. PLoS One. 2017 Jan 20;12(1):e0169805. doi: 10.1371/journal.pone.0169805. eCollection 2017. PLoS One. 2017. PMID: 28107457 Free PMC article.
The immunological mechanisms that control pneumococcal carriage.
Jochems SP, Weiser JN, Malley R, Ferreira DM. Jochems SP, et al. PLoS Pathog. 2017 Dec 21;13(12):e1006665. doi: 10.1371/journal.ppat.1006665. eCollection 2017 Dec. PLoS Pathog. 2017. PMID: 29267378 Free PMC article. Review.
Hands are vehicles for transmission of Streptococcus pneumoniae in novel controlled human infection study.
Connor V, German E, Pojar S, Mitsi E, Hales C, Nikolaou E, Hyder-Wright A, Adler H, Zaidi S, Hill H, Jochems SP, Burhan H, French N, Tobery T, Rylance J, Ferreira DM. Connor V, et al. Among authors: jochems sp. Eur Respir J. 2018 Oct 10;52(4):1800599. doi: 10.1183/13993003.00599-2018. Print 2018 Oct. Eur Respir J. 2018. PMID: 30305331 Free article. No abstract available.
Inflammation induced by influenza virus impairs human innate immune control of pneumococcus.
Jochems SP, Marcon F, Carniel BF, Holloway M, Mitsi E, Smith E, Gritzfeld JF, Solórzano C, Reiné J, Pojar S, Nikolaou E, German EL, Hyder-Wright A, Hill H, Hales C, de Steenhuijsen Piters WAA, Bogaert D, Adler H, Zaidi S, Connor V, Gordon SB, Rylance J, Nakaya HI, Ferreira DM. Jochems SP, et al. Nat Immunol. 2018 Dec;19(12):1299-1308. doi: 10.1038/s41590-018-0231-y. Epub 2018 Oct 29. Nat Immunol. 2018. PMID: 30374129 Free PMC article. Clinical Trial.
Interaction between the nasal microbiota and S. pneumoniae in the context of live-attenuated influenza vaccine.
de Steenhuijsen Piters WAA, Jochems SP, Mitsi E, Rylance J, Pojar S, Nikolaou E, German EL, Holloway M, Carniel BF, Chu MLJN, Arp K, Sanders EAM, Ferreira DM, Bogaert D. de Steenhuijsen Piters WAA, et al. Among authors: jochems sp. Nat Commun. 2019 Jul 5;10(1):2981. doi: 10.1038/s41467-019-10814-9. Nat Commun. 2019. PMID: 31278315 Free PMC article.
51 results