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Year | Number of Results |
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2019 | 1 |
2020 | 1 |
2021 | 2 |
2024 | 0 |
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Page 1
Structure-Guided Design of a "Bump-and-Hole" Bromodomain-Based Degradation Tag.
J Med Chem. 2021 Aug 12;64(15):11637-11650. doi: 10.1021/acs.jmedchem.1c00958. Epub 2021 Jul 19.
J Med Chem. 2021.
PMID: 34279939
A biphenyl inhibitor of eIF4E targeting an internal binding site enables the design of cell-permeable PROTAC-degraders.
Fischer PD, Papadopoulos E, Dempersmier JM, Wang ZF, Nowak RP, Donovan KA, Kalabathula J, Gorgulla C, Junghanns PPM, Kabha E, Dimitrakakis N, Petrov OI, Mitsiades C, Ducho C, Gelev V, Fischer ES, Wagner G, Arthanari H.
Fischer PD, et al. Among authors: kalabathula j.
Eur J Med Chem. 2021 Jul 5;219:113435. doi: 10.1016/j.ejmech.2021.113435. Epub 2021 Apr 8.
Eur J Med Chem. 2021.
PMID: 33892272
Free PMC article.
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Tubulin Resists Degradation by Cereblon-Recruiting PROTACs.
Gasic I, Groendyke BJ, Nowak RP, Yuan JC, Kalabathula J, Fischer ES, Gray NS, Mitchison TJ.
Gasic I, et al. Among authors: kalabathula j.
Cells. 2020 Apr 27;9(5):1083. doi: 10.3390/cells9051083.
Cells. 2020.
PMID: 32349222
Free PMC article.
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Small molecule degraders of the hepatitis C virus protease reduce susceptibility to resistance mutations.
de Wispelaere M, Du G, Donovan KA, Zhang T, Eleuteri NA, Yuan JC, Kalabathula J, Nowak RP, Fischer ES, Gray NS, Yang PL.
de Wispelaere M, et al. Among authors: kalabathula j.
Nat Commun. 2019 Aug 1;10(1):3468. doi: 10.1038/s41467-019-11429-w.
Nat Commun. 2019.
PMID: 31371704
Free PMC article.
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