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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 2
2005 2
2006 1
2007 1
2008 1
2009 1
2010 1
2012 1
2014 2
2015 1
2016 1
2017 2
2018 5
2019 1
2020 5
2021 2
2022 2
2023 3
2024 0

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33 results

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Page 1
In vitro evaluation of NA1-115-7-loaded nanoemulsions, an MCL-1-specific inhibitor of natural origin, intended to treat B-cell lymphoproliferative disorders after oral administration.
Séguy L, Daressy F, Lahlil S, Corvaisier S, Dumontet V, Litaudon M, Apel C, Roussi F, Wiels J, Robert A, Groo AC, Malzert-Fréon A. Séguy L, et al. Among authors: wiels j. Int J Pharm. 2023 Jan 5;630:122433. doi: 10.1016/j.ijpharm.2022.122433. Epub 2022 Nov 24. Int J Pharm. 2023. PMID: 36436745
NA1-115-7, from Zygogynum pancheri, is a new selective MCL-1 inhibitor inducing the apoptosis of hematological cancer cells but non-toxic to normal blood cells or cardiomyocytes.
Daressy F, Séguy L, Favre L, Corvaisier S, Apel C, Groo AC, Litaudon M, Dumontet V, Malzert-Fréon A, Desrat S, Roussi F, Robert A, Wiels J. Daressy F, et al. Among authors: wiels j. Biomed Pharmacother. 2022 Oct;154:113546. doi: 10.1016/j.biopha.2022.113546. Epub 2022 Aug 18. Biomed Pharmacother. 2022. PMID: 35988426 Free article.
Shiga Toxins as Antitumor Tools.
Robert A, Wiels J. Robert A, et al. Among authors: wiels j. Toxins (Basel). 2021 Sep 28;13(10):690. doi: 10.3390/toxins13100690. Toxins (Basel). 2021. PMID: 34678982 Free PMC article. Review.
Drimane Derivatives as the First Examples of Covalent BH3 Mimetics that Target MCL-1.
Daressy F, Malard F, Seguy L, Guérineau V, Apel C, Dumontet V, Robert A, Groo AC, Litaudon M, Bignon J, Desrat S, Malzert-Fréon A, Wiels J, Lescop E, Roussi F. Daressy F, et al. Among authors: wiels j. ChemMedChem. 2021 Jun 7;16(11):1788-1797. doi: 10.1002/cmdc.202100011. Epub 2021 Mar 23. ChemMedChem. 2021. PMID: 33665938
Oncogenic Properties of the EBV ZEBRA Protein.
Germini D, Sall FB, Shmakova A, Wiels J, Dokudovskaya S, Drouet E, Vassetzky Y. Germini D, et al. Among authors: wiels j. Cancers (Basel). 2020 Jun 5;12(6):1479. doi: 10.3390/cancers12061479. Cancers (Basel). 2020. PMID: 32517128 Free PMC article. Review.
Correction: Transient stabilization, rather than inhibition, of MYC amplifies extrinsic apoptosis and therapeutic responses in refractory B-cell lymphoma.
Harrington CT, Sotillo E, Robert A, Hayer KE, Bogusz AM, Psathas J, Yu D, Taylor D, Dang CV, Klein PS, Hogarty MD, Geoerger B, El-Deiry WS, Wiels J, Thomas-Tikhonenko A. Harrington CT, et al. Among authors: wiels j. Leukemia. 2020 May;34(5):1485. doi: 10.1038/s41375-019-0650-2. Leukemia. 2020. PMID: 31758088
33 results