Jin N - Search Results

1

A protein network map of head and neck cancer reveals PIK3CA mutant drug sensitivity.

Swaney DL, Ramms DJ, Wang Z, Park J, Goto Y, Soucheray M, Bhola N, Kim K, Zheng F, Zeng Y, McGregor M, Herrington KA, O'Keefe R, Jin N, VanLandingham NK, Foussard H, Von Dollen J, Bouhaddou M, Jimenez-Morales D, Obernier K, Kreisberg JF, Kim M, Johnson DE, Jura N, Grandis JR, Gutkind JS, Ideker T, Krogan NJ. Swaney DL, et al. Among authors: jin n. Science. 2021 Oct;374(6563):eabf2911. doi: 10.1126/science.abf2911. Epub 2021 Oct 1. Science. 2021. PMID: 34591642 Free PMC article.

2

Alterations and molecular targeting of the GSK-3 regulator, PI3K, in head and neck cancer.

Lee MJ, Jin N, Grandis JR, Johnson DE. Lee MJ, et al. Among authors: jin n. Biochim Biophys Acta Mol Cell Res. 2020 Jun;1867(6):118679. doi: 10.1016/j.bbamcr.2020.118679. Epub 2020 Feb 19. Biochim Biophys Acta Mol Cell Res. 2020. PMID: 32061630 Free PMC article. Review.

3

Therapeutic implications of activating noncanonical PIK3CA mutations in head and neck squamous cell carcinoma.

Jin N, Keam B, Cho J, Lee MJ, Kim HR, Torosyan H, Jura N, Ng PK, Mills GB, Li H, Zeng Y, Barbash Z, Tarcic G, Kang H, Bauman JE, Kim MO, VanLandingham NK, Swaney DL, Krogan NJ, Johnson DE, Grandis JR. Jin N, et al. J Clin Invest. 2021 Nov 15;131(22):e150335. doi: 10.1172/JCI150335. J Clin Invest. 2021. PMID: 34779417 Free PMC article.

4

Identification of metabolic vulnerabilities of receptor tyrosine kinases-driven cancer.

Jin N, Bi A, Lan X, Xu J, Wang X, Liu Y, Wang T, Tang S, Zeng H, Chen Z, Tan M, Ai J, Xie H, Zhang T, Liu D, Huang R, Song Y, Leung EL, Yao X, Ding J, Geng M, Lin SH, Huang M. Jin N, et al. Nat Commun. 2019 Jun 20;10(1):2701. doi: 10.1038/s41467-019-10427-2. Nat Commun. 2019. PMID: 31221965 Free PMC article.

5

Macroautophagy supports Sonic Hedgehog signaling by promoting Patched1 degradation.

Yang X, Jin N, Wang Y, Yao Y, Wang Y, Li T, Liu C, Yu T, Yin H, Zhang Z, Cheng SY, Yue S. Yang X, et al. Among authors: jin n. Biochim Biophys Acta Mol Cell Res. 2021 Nov;1868(12):119124. doi: 10.1016/j.bbamcr.2021.119124. Epub 2021 Aug 20. Biochim Biophys Acta Mol Cell Res. 2021. PMID: 34419491 Free article.

6

Cross talk between PI3K-AKT-GSK-3β and PP2A pathways determines tau hyperphosphorylation.

Wang Y, Yang R, Gu J, Yin X, Jin N, Xie S, Wang Y, Chang H, Qian W, Shi J, Iqbal K, Gong CX, Cheng C, Liu F. Wang Y, et al. Among authors: jin n. Neurobiol Aging. 2015 Jan;36(1):188-200. doi: 10.1016/j.neurobiolaging.2014.07.035. Epub 2014 Aug 1. Neurobiol Aging. 2015. PMID: 25219467

7

JX06 Selectively Inhibits Pyruvate Dehydrogenase Kinase PDK1 by a Covalent Cysteine Modification.

Sun W, Xie Z, Liu Y, Zhao D, Wu Z, Zhang D, Lv H, Tang S, Jin N, Jiang H, Tan M, Ding J, Luo C, Li J, Huang M, Geng M. Sun W, et al. Among authors: jin n. Cancer Res. 2015 Nov 15;75(22):4923-36. doi: 10.1158/0008-5472.CAN-15-1023. Epub 2015 Oct 19. Cancer Res. 2015. PMID: 26483203

8

Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer.

Zeng H, Qu J, Jin N, Xu J, Lin C, Chen Y, Yang X, He X, Tang S, Lan X, Yang X, Chen Z, Huang M, Ding J, Geng M. Zeng H, et al. Among authors: jin n. Cancer Cell. 2016 Sep 12;30(3):459-473. doi: 10.1016/j.ccell.2016.08.001. Cancer Cell. 2016. PMID: 27622335 Free article.

9

Phosphoglycerate mutase 1 regulates dNTP pool and promotes homologous recombination repair in cancer cells.

Qu J, Sun W, Zhong J, Lv H, Zhu M, Xu J, Jin N, Xie Z, Tan M, Lin SH, Geng M, Ding J, Huang M. Qu J, et al. Among authors: jin n. J Cell Biol. 2017 Feb;216(2):409-424. doi: 10.1083/jcb.201607008. Epub 2017 Jan 25. J Cell Biol. 2017. PMID: 28122957 Free PMC article.

10

Phosphoglycerate mutase 1 promotes cancer cell migration independent of its metabolic activity.

Zhang D, Jin N, Sun W, Li X, Liu B, Xie Z, Qu J, Xu J, Yang X, Su Y, Tang S, Han H, Chen D, Ding J, Tan M, Huang M, Geng M. Zhang D, et al. Among authors: jin n. Oncogene. 2017 May 18;36(20):2900-2909. doi: 10.1038/onc.2016.446. Epub 2016 Dec 19. Oncogene. 2017. PMID: 27991922

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