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Combining the rapid MTT formazan exocytosis assay and the MC65 protection assay led to the discovery of carbazole analogs as small molecule inhibitors of Abeta oligomer-induced cytotoxicity.
Hong HS, Maezawa I, Yao N, Xu B, Diaz-Avalos R, Rana S, Hua DH, Cheng RH, Lam KS, Jin LW. Hong HS, et al. Among authors: jin lw. Brain Res. 2007 Jan 26;1130(1):223-34. doi: 10.1016/j.brainres.2006.10.093. Epub 2006 Dec 8. Brain Res. 2007. PMID: 17157826 Free PMC article.
Congo red and thioflavin-T analogs detect Abeta oligomers.
Maezawa I, Hong HS, Liu R, Wu CY, Cheng RH, Kung MP, Kung HF, Lam KS, Oddo S, Laferla FM, Jin LW. Maezawa I, et al. Among authors: jin lw. J Neurochem. 2008 Jan;104(2):457-68. doi: 10.1111/j.1471-4159.2007.04972.x. Epub 2007 Oct 22. J Neurochem. 2008. PMID: 17953662 Free article.
199 results