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A fly GWAS for purine metabolites identifies human FAM214 homolog medusa, which acts in a conserved manner to enhance hyperuricemia-driven pathologies by modulating purine metabolism and the inflammatory response.
Hilsabeck TAU, Liu-Bryan R, Guo T, Wilson KA, Bose N, Raftery D, Beck JN, Lang S, Jin K, Nelson CS, Oron T, Stoller M, Promislow D, Brem RB, Terkeltaub R, Kapahi P. Hilsabeck TAU, et al. Among authors: jin k. Geroscience. 2022 Aug;44(4):2195-2211. doi: 10.1007/s11357-022-00557-9. Epub 2022 Apr 6. Geroscience. 2022. PMID: 35381951 Free PMC article.
DNA methylation and chromatin accessibility predict age in the domestic dog.
Jin K, McCoy BM, Goldman EA, Usova V, Tkachev V, Chitsazan AD, Kakebeen A, Jeffery U, Creevy KE, Wills A, Snyder-Mackler N, Promislow DEL. Jin K, et al. Aging Cell. 2024 Apr;23(4):e14079. doi: 10.1111/acel.14079. Epub 2024 Jan 23. Aging Cell. 2024. PMID: 38263575 Free PMC article.
2,804 results