Jin J - Search Results

1

Non-canonical function of histone methyltransferase G9a in the translational regulation of chronic inflammation.

Muneer A, Wang L, Xie L, Zhang F, Wu B, Mei L, Lenarcic EM, Feng EH, Song J, Xiong Y, Yu X, Wang C, Jain K, Strahl BD, Cook JG, Wan YY, Moorman NJ, Song H, Jin J, Chen X. Muneer A, et al. Among authors: jin j. Cell Chem Biol. 2023 Dec 21;30(12):1525-1541.e7. doi: 10.1016/j.chembiol.2023.09.012. Epub 2023 Oct 19. Cell Chem Biol. 2023. PMID: 37858336

2

Discovery of an in vivo chemical probe of the lysine methyltransferases G9a and GLP.

Liu F, Barsyte-Lovejoy D, Li F, Xiong Y, Korboukh V, Huang XP, Allali-Hassani A, Janzen WP, Roth BL, Frye SV, Arrowsmith CH, Brown PJ, Vedadi M, Jin J. Liu F, et al. Among authors: jin j. J Med Chem. 2013 Nov 14;56(21):8931-42. doi: 10.1021/jm401480r. Epub 2013 Oct 31. J Med Chem. 2013. PMID: 24102134 Free PMC article.

3

A chromatin activity-based chemoproteomic approach reveals a transcriptional repressome for gene-specific silencing.

Liu C, Yu Y, Liu F, Wei X, Wrobel JA, Gunawardena HP, Zhou L, Jin J, Chen X. Liu C, et al. Among authors: jin j. Nat Commun. 2014 Dec 15;5:5733. doi: 10.1038/ncomms6733. Nat Commun. 2014. PMID: 25502336 Free PMC article.

4

Structure-activity relationship studies of SETD8 inhibitors.

Ma A, Yu W, Xiong Y, Butler KV, Brown PJ, Jin J. Ma A, et al. Among authors: jin j. Medchemcomm. 2014 Dec;5(12):1892-1898. doi: 10.1039/C4MD00317A. Medchemcomm. 2014. PMID: 25554733 Free PMC article.

5

Non-canonical Bromodomain within DNA-PKcs Promotes DNA Damage Response and Radioresistance through Recognizing an IR-Induced Acetyl-Lysine on H2AX.

Wang L, Xie L, Ramachandran S, Lee Y, Yan Z, Zhou L, Krajewski K, Liu F, Zhu C, Chen DJ, Strahl BD, Jin J, Dokholyan NV, Chen X. Wang L, et al. Among authors: jin j. Chem Biol. 2015 Jul 23;22(7):849-61. doi: 10.1016/j.chembiol.2015.05.014. Epub 2015 Jun 25. Chem Biol. 2015. PMID: 26119999 Free PMC article.

6

A Role for Widely Interspaced Zinc Finger (WIZ) in Retention of the G9a Methyltransferase on Chromatin.

Simon JM, Parker JS, Liu F, Rothbart SB, Ait-Si-Ali S, Strahl BD, Jin J, Davis IJ, Mosley AL, Pattenden SG. Simon JM, et al. Among authors: jin j. J Biol Chem. 2015 Oct 23;290(43):26088-102. doi: 10.1074/jbc.M115.654459. Epub 2015 Sep 3. J Biol Chem. 2015. PMID: 26338712 Free PMC article.

7

Targeting the histone methyltransferase G9a activates imprinted genes and improves survival of a mouse model of Prader-Willi syndrome.

Kim Y, Lee HM, Xiong Y, Sciaky N, Hulbert SW, Cao X, Everitt JI, Jin J, Roth BL, Jiang YH. Kim Y, et al. Among authors: jin j. Nat Med. 2017 Feb;23(2):213-222. doi: 10.1038/nm.4257. Epub 2016 Dec 26. Nat Med. 2017. PMID: 28024084 Free PMC article.

8

Discovery of Potent and Selective Inhibitors for G9a-Like Protein (GLP) Lysine Methyltransferase.

Xiong Y, Li F, Babault N, Dong A, Zeng H, Wu H, Chen X, Arrowsmith CH, Brown PJ, Liu J, Vedadi M, Jin J. Xiong Y, et al. Among authors: jin j. J Med Chem. 2017 Mar 9;60(5):1876-1891. doi: 10.1021/acs.jmedchem.6b01645. Epub 2017 Feb 14. J Med Chem. 2017. PMID: 28135087 Free PMC article.

9

Structure-activity relationship studies of G9a-like protein (GLP) inhibitors.

Xiong Y, Li F, Babault N, Wu H, Dong A, Zeng H, Chen X, Arrowsmith CH, Brown PJ, Liu J, Vedadi M, Jin J. Xiong Y, et al. Among authors: jin j. Bioorg Med Chem. 2017 Aug 15;25(16):4414-4423. doi: 10.1016/j.bmc.2017.06.021. Epub 2017 Jun 19. Bioorg Med Chem. 2017. PMID: 28662962 Free PMC article.

10

Inhibition of the G9a/GLP histone methyltransferase complex modulates anxiety-related behavior in mice.

Wang DY, Kosowan J, Samsom J, Leung L, Zhang KL, Li YX, Xiong Y, Jin J, Petronis A, Oh G, Wong AHC. Wang DY, et al. Among authors: jin j. Acta Pharmacol Sin. 2018 May;39(5):866-874. doi: 10.1038/aps.2017.190. Epub 2018 Feb 8. Acta Pharmacol Sin. 2018. PMID: 29417943 Free PMC article.

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