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Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol.
van Kuijk K, McCracken IR, Tillie RJHA, Asselberghs SEJ, Kheder DA, Muitjens S, Jin H, Taylor RS, Wichers Schreur R, Kuppe C, Dobie R, Ramachandran P, Gijbels MJ, Temmerman L, Kirkwoord PM, Luyten J, Li Y, Noels H, Goossens P, Wilson-Kanamori JR, Schurgers LJ, Shen YH, Mees BME, Biessen EAL, Henderson NC, Kramann R, Baker AH, Sluimer JC. van Kuijk K, et al. Among authors: jin h. Cardiovasc Res. 2023 Jul 4;119(7):1509-1523. doi: 10.1093/cvr/cvad016. Cardiovasc Res. 2023. PMID: 36718802 Free PMC article.
Low human and murine Mcl-1 expression leads to a pro-apoptotic plaque phenotype enriched in giant-cells.
Fontaine MAC, Westra MM, Bot I, Jin H, Franssen AJPM, Bot M, de Jager SCA, Dzhagalov I, He YW, van Vlijmen BJM, Gijbels MJJ, Reutelingsperger CP, van Berkel TJC, Sluimer JC, Temmerman L, Biessen EAL. Fontaine MAC, et al. Among authors: jin h. Sci Rep. 2019 Oct 10;9(1):14547. doi: 10.1038/s41598-019-51020-3. Sci Rep. 2019. PMID: 31601924 Free PMC article.
The hypoxia-sensor carbonic anhydrase IX affects macrophage metabolism, but is not a suitable biomarker for human cardiovascular disease.
Demandt JAF, Dubois LJ, van Kuijk K, Zaťovičová M, Jin H, Parkkila S, van der Laan SW, Jelenska L, Mees BME, Reutelingsperger CPM, Cleutjens KBJM, van der Kallen CJH, Schalkwijk CG, van Greevenbroek MMJ, Biessen EAL, Pasterkamp G, Pastoreková S, Stehouwer CDA, Sluimer JC. Demandt JAF, et al. Among authors: jin h. Sci Rep. 2021 Jan 11;11(1):425. doi: 10.1038/s41598-020-79978-5. Sci Rep. 2021. PMID: 33432108 Free PMC article.
Deficiency of myeloid PHD proteins aggravates atherogenesis via macrophage apoptosis and paracrine fibrotic signalling.
van Kuijk K, Demandt JAF, Perales-Patón J, Theelen TL, Kuppe C, Marsch E, de Bruijn J, Jin H, Gijbels MJ, Matic L, Mees BME, Reutelingsperger CPM, Hedin U, Biessen EAL, Carmeliet P, Baker AH, Kramann RK, Schurgers LJ, Saez-Rodriguez J, Sluimer JC. van Kuijk K, et al. Among authors: jin h. Cardiovasc Res. 2022 Mar 25;118(5):1232-1246. doi: 10.1093/cvr/cvab152. Cardiovasc Res. 2022. PMID: 33913468 Free PMC article.
Integrative multiomics analysis of human atherosclerosis reveals a serum response factor-driven network associated with intraplaque hemorrhage.
Jin H, Goossens P, Juhasz P, Eijgelaar W, Manca M, Karel JMH, Smirnov E, Sikkink CJJM, Mees BME, Waring O, van Kuijk K, Fazzi GE, Gijbels MJJ, Kutmon M, Evelo CTA, Hedin U, Daemen MJAP, Sluimer JC, Matic L, Biessen EAL. Jin H, et al. Clin Transl Med. 2021 Jun;11(6):e458. doi: 10.1002/ctm2.458. Clin Transl Med. 2021. PMID: 34185408 Free PMC article.
Protective role of chaperone-mediated autophagy against atherosclerosis.
Madrigal-Matute J, de Bruijn J, van Kuijk K, Riascos-Bernal DF, Diaz A, Tasset I, Martín-Segura A, Gijbels MJJ, Sander B, Kaushik S, Biessen EAL, Tiano S, Bourdenx M, Krause GJ, McCracken I, Baker AH, Jin H, Sibinga NES, Bravo-Cordero JJ, Macian F, Singh R, Rensen PCN, Berbée JFP, Pasterkamp G, Sluimer JC, Cuervo AM. Madrigal-Matute J, et al. Among authors: jin h. Proc Natl Acad Sci U S A. 2022 Apr 5;119(14):e2121133119. doi: 10.1073/pnas.2121133119. Epub 2022 Apr 1. Proc Natl Acad Sci U S A. 2022. PMID: 35363568 Free PMC article.
Pro-oxidative priming but maintained cardiac function in a broad spectrum of murine models of chronic kidney disease.
Wollenhaupt J, Frisch J, Harlacher E, Wong DWL, Jin H, Schulte C, Vondenhoff S, Moellmann J, Klinkhammer BM, Zhang L, Baleanu-Curaj A, Liehn EA, Speer T, Kazakov A, Werner C, van der Vorst EPC, Selejan SR, Hohl M, Böhm M, Kramann R, Biessen EAL, Lehrke M, Marx N, Jankowski J, Maack C, Boor P, Prates Roma L, Noels H. Wollenhaupt J, et al. Among authors: jin h. Redox Biol. 2022 Oct;56:102459. doi: 10.1016/j.redox.2022.102459. Epub 2022 Aug 30. Redox Biol. 2022. PMID: 36099852 Free PMC article.
Blood Milieu in Acute Myocardial Infarction Reprograms Human Macrophages for Trauma Repair.
Fontaine MAC, Jin H, Gagliardi M, Rousch M, Wijnands E, Stoll M, Li X, Schurgers L, Reutelingsperger C, Schalkwijk C, van den Akker NMS, Molin DGM, Gullestad L, Eritsland J, Hoffman P, Skjelland M, Andersen GØ, Aukrust P, Karel J, Smirnov E, Halvorsen B, Temmerman L, Biessen EAL. Fontaine MAC, et al. Among authors: jin h. Adv Sci (Weinh). 2023 Feb;10(5):e2203053. doi: 10.1002/advs.202203053. Epub 2022 Dec 16. Adv Sci (Weinh). 2023. PMID: 36526599 Free PMC article.
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