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Inflammasome activation: from molecular mechanisms to autoinflammation.
Clin Transl Immunology. 2022 Jul 7;11(7):e1404. doi: 10.1002/cti2.1404. eCollection 2022.
Clin Transl Immunology. 2022.
PMID: 35832835
Free PMC article.
Review.
STING activation promotes robust immune response and NK cell-mediated tumor regression in glioblastoma models.
Berger G, Knelson EH, Jimenez-Macias JL, Nowicki MO, Han S, Panagioti E, Lizotte PH, Adu-Berchie K, Stafford A, Dimitrakakis N, Zhou L, Chiocca EA, Mooney DJ, Barbie DA, Lawler SE.
Berger G, et al. Among authors: jimenez macias jl.
Proc Natl Acad Sci U S A. 2022 Jul 12;119(28):e2111003119. doi: 10.1073/pnas.2111003119. Epub 2022 Jul 5.
Proc Natl Acad Sci U S A. 2022.
PMID: 35787058
Free PMC article.
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PPRX-1701, a nanoparticle formulation of 6'-bromoindirubin acetoxime, improves delivery and shows efficacy in preclinical GBM models.
Zdioruk M, Jimenez-Macias JL, Nowicki MO, Manz KE, Pennell KD, Koch MS, Finkelberg T, Wu B, Boucher P, Takeda Y, Li W, Piranlioglu R, Ling AL, Chiocca EA, Lawler SE.
Zdioruk M, et al. Among authors: jimenez macias jl.
Cell Rep Med. 2023 May 16;4(5):101019. doi: 10.1016/j.xcrm.2023.101019. Epub 2023 Apr 14.
Cell Rep Med. 2023.
PMID: 37060903
Free PMC article.
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A Pt(IV)-conjugated brain penetrant macrocyclic peptide shows pre-clinical efficacy in glioblastoma.
Jimenez-Macias JL, Lee YC, Miller E, Finkelberg T, Zdioruk M, Berger G, Farquhar CE, Nowicki MO, Cho CF, Fedeles BI, Loas A, Pentelute BL, Lawler SE.
Jimenez-Macias JL, et al.
J Control Release. 2022 Dec;352:623-636. doi: 10.1016/j.jconrel.2022.10.051. Epub 2022 Nov 4.
J Control Release. 2022.
PMID: 36349615
Free PMC article.
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Ultrasound-triggered therapeutic microbubbles enhance the efficacy of cytotoxic drugs by increasing circulation and tumor drug accumulation and limiting bioavailability and toxicity in normal tissues.
Ingram N, McVeigh LE, Abou-Saleh RH, Maynard J, Peyman SA, McLaughlan JR, Fairclough M, Marston G, Valleley EMA, Jimenez-Macias JL, Charalambous A, Townley W, Haddrick M, Wierzbicki A, Wright A, Volpato M, Simpson PB, Treanor DE, Thomson NH, Loadman PM, Bushby RJ, Johnson BRG, Jones PF, Evans JA, Freear S, Markham AF, Evans SD, Coletta PL.
Ingram N, et al. Among authors: jimenez macias jl.
Theranostics. 2020 Sep 1;10(24):10973-10992. doi: 10.7150/thno.49670. eCollection 2020.
Theranostics. 2020.
PMID: 33042265
Free PMC article.
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