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A hotspot for posttranslational modifications on the androgen receptor dimer interface drives pathology and anti-androgen resistance.
Sci Adv. 2023 Mar 17;9(11):eade2175. doi: 10.1126/sciadv.ade2175. Epub 2023 Mar 15.
Sci Adv. 2023.
PMID: 36921044
Free PMC article.
The multivalency of the glucocorticoid receptor ligand-binding domain explains its manifold physiological activities.
Jiménez-Panizo A, Alegre-Martí A, Tettey TT, Fettweis G, Abella M, Antón R, Johnson TA, Kim S, Schiltz RL, Núñez-Barrios I, Font-Díaz J, Caelles C, Valledor AF, Pérez P, Rojas AM, Fernández-Recio J, Presman DM, Hager GL, Fuentes-Prior P, Estébanez-Perpiñá E.
Jiménez-Panizo A, et al.
Nucleic Acids Res. 2022 Dec 9;50(22):13063-13082. doi: 10.1093/nar/gkac1119.
Nucleic Acids Res. 2022.
PMID: 36464162
Free PMC article.
Item in Clipboard
Oleic acid is an endogenous ligand of TLX/NR2E1 that triggers hippocampal neurogenesis.
Kandel P, Semerci F, Mishra R, Choi W, Bajic A, Baluya D, Ma L, Chen K, Cao AC, Phongmekhin T, Matinyan N, Jiménez-Panizo A, Chamakuri S, Raji IO, Chang L, Fuentes-Prior P, MacKenzie KR, Benn CL, Estébanez-Perpiñá E, Venken K, Moore DD, Young DW, Maletic-Savatic M.
Kandel P, et al. Among authors: jimenez panizo a.
Proc Natl Acad Sci U S A. 2022 Mar 29;119(13):e2023784119. doi: 10.1073/pnas.2023784119. Epub 2022 Mar 25.
Proc Natl Acad Sci U S A. 2022.
PMID: 35333654
Free PMC article.
Item in Clipboard
Glucocorticoid Resistance: Interference between the Glucocorticoid Receptor and the MAPK Signalling Pathways.
Sevilla LM, Jiménez-Panizo A, Alegre-Martí A, Estébanez-Perpiñá E, Caelles C, Pérez P.
Sevilla LM, et al. Among authors: jimenez panizo a.
Int J Mol Sci. 2021 Sep 17;22(18):10049. doi: 10.3390/ijms221810049.
Int J Mol Sci. 2021.
PMID: 34576214
Free PMC article.
Review.
Item in Clipboard
Nuclear receptors: Lipid and hormone sensors with essential roles in the control of cancer development.
Font-Díaz J, Jiménez-Panizo A, Caelles C, Vivanco MD, Pérez P, Aranda A, Estébanez-Perpiñá E, Castrillo A, Ricote M, Valledor AF.
Font-Díaz J, et al. Among authors: jimenez panizo a.
Semin Cancer Biol. 2021 Aug;73:58-75. doi: 10.1016/j.semcancer.2020.12.007. Epub 2020 Dec 9.
Semin Cancer Biol. 2021.
PMID: 33309851
Review.
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Non-canonical dimerization of the androgen receptor and other nuclear receptors: implications for human disease.
Jiménez-Panizo A, Pérez P, Rojas AM, Fuentes-Prior P, Estébanez-Perpiñá E.
Jiménez-Panizo A, et al.
Endocr Relat Cancer. 2019 Aug;26(8):R479-R497. doi: 10.1530/ERC-19-0132.
Endocr Relat Cancer. 2019.
PMID: 31252411
Free article.
Review.
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