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MicroRNA-654-5p suppresses ovarian cancer development impacting on MYC, WNT and AKT pathways.
Majem B, Parrilla A, Jiménez C, Suárez-Cabrera L, Barber M, Marín A, Castellví J, Tamayo G, Moreno-Bueno G, Ponce J, Matias-Guiu X, Alameda F, Romero I, Sánchez JL, Pérez-Benavente A, Moran S, Esteller M, Reventós J, Rigau M, Gil-Moreno A, Segura MF, Santamaría A. Majem B, et al. Among authors: jimenez c. Oncogene. 2019 Aug;38(32):6035-6050. doi: 10.1038/s41388-019-0860-0. Epub 2019 Jul 5. Oncogene. 2019. PMID: 31278368
Targeting of epigenetic regulators in neuroblastoma.
Jubierre L, Jiménez C, Rovira E, Soriano A, Sábado C, Gros L, Llort A, Hladun R, Roma J, Toledo JS, Gallego S, Segura MF. Jubierre L, et al. Among authors: jimenez c. Exp Mol Med. 2018 Apr 27;50(4):1-12. doi: 10.1038/s12276-018-0077-2. Exp Mol Med. 2018. PMID: 29700278 Free PMC article. Review.
Functional high-throughput screening reveals miR-323a-5p and miR-342-5p as new tumor-suppressive microRNA for neuroblastoma.
Soriano A, Masanas M, Boloix A, Masiá N, París-Coderch L, Piskareva O, Jiménez C, Henrich KO, Roma J, Westermann F, Stallings RL, Sábado C, de Toledo JS, Santamaria A, Gallego S, Segura MF. Soriano A, et al. Among authors: jimenez c. Cell Mol Life Sci. 2019 Jun;76(11):2231-2243. doi: 10.1007/s00018-019-03041-4. Epub 2019 Feb 15. Cell Mol Life Sci. 2019. PMID: 30770954 Free PMC article.
CN133, a Novel Brain-Penetrating Histone Deacetylase Inhibitor, Hampers Tumor Growth in Patient-Derived Pediatric Posterior Fossa Ependymoma Models.
Antonelli R, Jiménez C, Riley M, Servidei T, Riccardi R, Soriano A, Roma J, Martínez-Saez E, Martini M, Ruggiero A, Moreno L, Sánchez de Toledo J, Gallego S, Bové J, Hooker JM, Segura MF. Antonelli R, et al. Among authors: jimenez c. Cancers (Basel). 2020 Jul 16;12(7):1922. doi: 10.3390/cancers12071922. Cancers (Basel). 2020. PMID: 32708733 Free PMC article.
The antitumour drug ABTL0812 impairs neuroblastoma growth through endoplasmic reticulum stress-mediated autophagy and apoptosis.
París-Coderch L, Soriano A, Jiménez C, Erazo T, Muñoz-Guardiola P, Masanas M, Antonelli R, Boloix A, Alfón J, Pérez-Montoyo H, Yeste-Velasco M, Domènech C, Roma J, Sánchez de Toledo J, Moreno L, Lizcano JM, Gallego S, Segura MF. París-Coderch L, et al. Among authors: jimenez c. Cell Death Dis. 2020 Sep 17;11(9):773. doi: 10.1038/s41419-020-02986-w. Cell Death Dis. 2020. PMID: 32943619 Free PMC article.
Neuronal Differentiation-Related Epigenetic Regulator ZRF1 Has Independent Prognostic Value in Neuroblastoma but Is Functionally Dispensable In Vitro.
Jiménez C, Antonelli R, Masanas M, Soriano A, Devis-Jauregui L, Camacho J, Magdaleno A, Guillén G, Hladun R, Jubierre L, Roma J, Llobet-Navas D, Sánchez de Toledo J, Moreno L, Gallego S, Segura MF. Jiménez C, et al. Cancers (Basel). 2021 Sep 28;13(19):4845. doi: 10.3390/cancers13194845. Cancers (Basel). 2021. PMID: 34638328 Free PMC article.
The oral KIF11 inhibitor 4SC-205 exhibits antitumor activity and potentiates standard and targeted therapies in primary and metastatic neuroblastoma models.
Masanas M, Masiá N, Suárez-Cabrera L, Olivan M, Soriano A, Majem B, Devis-Jauregui L, Burgos-Panadero R, Jiménez C, Rodriguez-Sodupe P, Boloix A, Toledano I, Guillén G, Navarro A, Llobet-Navas D, Villanueva A, Sánchez de Toledo J, Roma J, Noguera R, Moreno L, Krauss R, Gallego S, Santamaria A, Segura MF. Masanas M, et al. Among authors: jimenez c. Clin Transl Med. 2021 Oct;11(10):e533. doi: 10.1002/ctm2.533. Clin Transl Med. 2021. PMID: 34709738 Free PMC article. No abstract available.
Methodological advances in the discovery of novel neuroblastoma therapeutics.
Segura MF, Soriano A, Roma J, Piskareva O, Jiménez C, Boloix A, Fletcher JI, Haber M, Gray JC, Cerdá-Alberich L, Martínez de Las Heras B, Cañete A, Gallego S, Moreno L. Segura MF, et al. Among authors: jimenez c. Expert Opin Drug Discov. 2022 Feb;17(2):167-179. doi: 10.1080/17460441.2022.2002297. Epub 2021 Nov 22. Expert Opin Drug Discov. 2022. PMID: 34807782 Review.
Structural disruption of BAF chromatin remodeller impairs neuroblastoma metastasis by reverting an invasiveness epigenomic program.
Jiménez C, Antonelli R, Nadal-Ribelles M, Devis-Jauregui L, Latorre P, Solé C, Masanas M, Molero-Valenzuela A, Soriano A, Sánchez de Toledo J, Llobet-Navas D, Roma J, Posas F, de Nadal E, Gallego S, Moreno L, Segura MF. Jiménez C, et al. Mol Cancer. 2022 Sep 3;21(1):175. doi: 10.1186/s12943-022-01643-4. Mol Cancer. 2022. PMID: 36057593 Free PMC article.
1,774 results