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The co-chaperone UNC45A is essential for the expression of mitotic kinase NEK7 and tumorigenesis.
Eisa NH, Jilani Y, Kainth K, Redd P, Lu S, Bougrine O, Abdul Sater H, Patwardhan CA, Shull A, Shi H, Liu K, Elsherbiny NM, Eissa LA, El-Shishtawy MM, Horuzsko A, Bollag R, Maihle N, Roig J, Korkaya H, Cowell JK, Chadli A. Eisa NH, et al. Among authors: jilani y. J Biol Chem. 2019 Apr 5;294(14):5246-5260. doi: 10.1074/jbc.RA118.006597. Epub 2019 Feb 8. J Biol Chem. 2019. PMID: 30737284 Free PMC article.
Enniatin A inhibits the chaperone Hsp90 and unleashes the immune system against triple-negative breast cancer.
Eisa NH, Crowley VM, Elahi A, Kommalapati VK, Serwetnyk MA, Llbiyi T, Lu S, Kainth K, Jilani Y, Marasco D, El Andaloussi A, Lee S, Tsai FTF, Rodriguez PC, Munn D, Celis E, Korkaya H, Debbab A, Blagg B, Chadli A. Eisa NH, et al. Among authors: jilani y. iScience. 2023 Oct 24;26(12):108308. doi: 10.1016/j.isci.2023.108308. eCollection 2023 Dec 15. iScience. 2023. PMID: 38025772 Free PMC article.