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Targeting STING oligomerization with small-molecule inhibitors.
Humphries F, Shmuel-Galia L, Jiang Z, Zhou JY, Barasa L, Mondal S, Wilson R, Sultana N, Shaffer SA, Ng SL, Pesiridis GS, Thompson PR, Fitzgerald KA. Humphries F, et al. Among authors: jiang z. Proc Natl Acad Sci U S A. 2023 Aug 15;120(33):e2305420120. doi: 10.1073/pnas.2305420120. Epub 2023 Aug 7. Proc Natl Acad Sci U S A. 2023. PMID: 37549268 Free PMC article.
Cell type-specific recognition of human metapneumoviruses (HMPVs) by retinoic acid-inducible gene I (RIG-I) and TLR7 and viral interference of RIG-I ligand recognition by HMPV-B1 phosphoprotein.
Goutagny N, Jiang Z, Tian J, Parroche P, Schickli J, Monks BG, Ulbrandt N, Ji H, Kiener PA, Coyle AJ, Fitzgerald KA. Goutagny N, et al. Among authors: jiang z. J Immunol. 2010 Feb 1;184(3):1168-79. doi: 10.4049/jimmunol.0902750. Epub 2009 Dec 30. J Immunol. 2010. PMID: 20042593 Free PMC article.
Mice lacking Tbk1 activity exhibit immune cell infiltrates in multiple tissues and increased susceptibility to LPS-induced lethality.
Marchlik E, Thakker P, Carlson T, Jiang Z, Ryan M, Marusic S, Goutagny N, Kuang W, Askew GR, Roberts V, Benoit S, Zhou T, Ling V, Pfeifer R, Stedman N, Fitzgerald KA, Lin LL, Hall JP. Marchlik E, et al. Among authors: jiang z. J Leukoc Biol. 2010 Dec;88(6):1171-80. doi: 10.1189/jlb.0210071. Epub 2010 Jul 22. J Leukoc Biol. 2010. PMID: 20651301
Structures of the HIN domain:DNA complexes reveal ligand binding and activation mechanisms of the AIM2 inflammasome and IFI16 receptor.
Jin T, Perry A, Jiang J, Smith P, Curry JA, Unterholzner L, Jiang Z, Horvath G, Rathinam VA, Johnstone RW, Hornung V, Latz E, Bowie AG, Fitzgerald KA, Xiao TS. Jin T, et al. Among authors: jiang j, jiang z. Immunity. 2012 Apr 20;36(4):561-71. doi: 10.1016/j.immuni.2012.02.014. Epub 2012 Apr 5. Immunity. 2012. PMID: 22483801 Free PMC article.
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