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Mitochondrial micropeptide MOXI promotes fibrotic gene transcription by translocation to the nucleus and bridging N-acetyltransferase 14 with transcription factor c-Jun.
Li J, Qu X, Guan C, Luo N, Chen H, Li A, Zhuang H, Yang J, Diao H, Zeng S, Wang Q, Fan J, Jiang M, Bai X, Ye Z, Jiang X, Chen W, Nikolic-Paterson DJ, Yu X. Li J, et al. Among authors: jiang m, jiang x. Kidney Int. 2023 May;103(5):886-902. doi: 10.1016/j.kint.2023.01.024. Epub 2023 Feb 15. Kidney Int. 2023. PMID: 36804379
The secreted micropeptide C4orf48 enhances renal fibrosis via an RNA-binding mechanism.
Yang J, Zhuang H, Li J, Nunez-Nescolarde AB, Luo N, Chen H, Li A, Qu X, Wang Q, Fan J, Bai X, Ye Z, Gu B, Meng Y, Zhang X, Wu D, Sia Y, Jiang X, Chen W, Combes AN, Nikolic-Paterson DJ, Yu X. Yang J, et al. Among authors: jiang x. J Clin Invest. 2024 Apr 16;134(10):e178392. doi: 10.1172/JCI178392. J Clin Invest. 2024. PMID: 38625739 Free PMC article.
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