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A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer.
Huang K, Liang Q, Zhou Y, Jiang LL, Gu WM, Luo MY, Tang YB, Wang Y, Lu W, Huang M, Zhang SZ, Zhuang GL, Dai Q, Shen QC, Zhang J, Lei HM, Zhu L, Ye DY, Chen HZ, Zhou L, Shen Y. Huang K, et al. Among authors: jiang ll. Cell Metab. 2019 Dec 3;30(6):1107-1119.e8. doi: 10.1016/j.cmet.2019.09.014. Epub 2019 Oct 10. Cell Metab. 2019. PMID: 31607564 Free article.
An allosteric PGAM1 inhibitor effectively suppresses pancreatic ductal adenocarcinoma.
Wen CL, Huang K, Jiang LL, Lu XX, Dai YT, Shi MM, Tang XM, Wang QB, Zhang XD, Wang PH, Li HT, Ruan XX, Wang LW, Wang XJ, Wang Q, Lu W, Xiang XQ, Sun X, Xu YH, Lai LH, Zhan Q, Li HW, Peng CH, Chen J, Huang JY, Ye DY, Chen SJ, Chen Z, Li M, Fang Y, Shen BY, Zhou L. Wen CL, et al. Among authors: jiang ll. Proc Natl Acad Sci U S A. 2019 Nov 12;116(46):23264-23273. doi: 10.1073/pnas.1914557116. Epub 2019 Oct 29. Proc Natl Acad Sci U S A. 2019. PMID: 31662475 Free PMC article.
Site-Selective Phosphoglycerate Mutase 1 Acetylation by a Small Molecule.
Zhang X, Jiang L, Huang K, Fang C, Li J, Yang J, Li H, Ruan X, Wang P, Mo M, Wu P, Xu Y, Peng C, Uesugi M, Ye D, Yu FX, Zhou L. Zhang X, et al. ACS Chem Biol. 2020 Mar 20;15(3):632-639. doi: 10.1021/acschembio.9b00962. Epub 2020 Feb 24. ACS Chem Biol. 2020. PMID: 32069008
Chemoproteomic Profiling of a Pharmacophore-Focused Chemical Library.
Punzalan LL, Jiang L, Mao D, Mahapatra AD, Sato S, Takemoto Y, Tsujimura M, Kusamori K, Nishikawa M, Zhou L, Uesugi M. Punzalan LL, et al. Among authors: jiang l. Cell Chem Biol. 2020 Jun 18;27(6):708-718.e10. doi: 10.1016/j.chembiol.2020.04.007. Epub 2020 May 12. Cell Chem Biol. 2020. PMID: 32402240 Free article.
A Novel Allosteric Inhibitor of Phosphoglycerate Mutase 1 Suppresses Growth and Metastasis of Non-Small-Cell Lung Cancer.
Huang K, Liang Q, Zhou Y, Jiang LL, Gu WM, Luo MY, Tang YB, Wang Y, Lu W, Huang M, Zhang SZ, Zhuang GL, Dai Q, Shen QC, Zhang J, Lei HM, Zhu L, Ye DY, Chen HZ, Zhou L, Shen Y. Huang K, et al. Among authors: jiang ll. Cell Metab. 2021 Jan 5;33(1):223. doi: 10.1016/j.cmet.2020.12.013. Cell Metab. 2021. PMID: 33406402 Free article. No abstract available.
416 results