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A bacterial extracellular vesicle-based intranasal vaccine against SARS-CoV-2 protects against disease and elicits neutralizing antibodies to wild-type and Delta variants.
Jiang L, Driedonks TAP, Jong WSP, Dhakal S, Bart van den Berg van Saparoea H, Sitaras I, Zhou R, Caputo C, Littlefield K, Lowman M, Chen M, Lima G, Gololobova O, Smith B, Mahairaki V, Riley Richardson M, Mulka KR, Lane AP, Klein SL, Pekosz A, Brayton C, Mankowski JL, Luirink J, Villano JS, Witwer KW. Jiang L, et al. J Extracell Vesicles. 2022 Mar;11(3):e12192. doi: 10.1002/jev2.12192. J Extracell Vesicles. 2022. PMID: 35289114 Free PMC article.
A post-insertion strategy for surface functionalization of bacterial and mammalian cell-derived extracellular vesicles.
Jiang L, Luirink J, Kooijmans SAA, van Kessel KPM, Jong W, van Essen M, Seinen CW, de Maat S, de Jong OG, Gitz-François JFF, Hennink WE, Vader P, Schiffelers RM. Jiang L, et al. Biochim Biophys Acta Gen Subj. 2021 Apr;1865(4):129763. doi: 10.1016/j.bbagen.2020.129763. Epub 2020 Oct 14. Biochim Biophys Acta Gen Subj. 2021. PMID: 33065252 Free article.
Pharmacokinetics and biodistribution of extracellular vesicles administered intravenously and intranasally to Macaca nemestrina.
Driedonks T, Jiang L, Carlson B, Han Z, Liu G, Queen SE, Shirk EN, Gololobova O, Liao Z, Nyberg LH, Lima G, Paniushkina L, Garcia-Contreras M, Schonvisky K, Castell N, Stover M, Guerrero-Martin S, Richardson R, Smith B, Machairaki V, Lai CP, Izzi JM, Hutchinson EK, Pate KAM, Witwer KW. Driedonks T, et al. Among authors: jiang l. J Extracell Biol. 2022 Oct;1(10):e59. doi: 10.1002/jex2.59. Epub 2022 Oct 11. J Extracell Biol. 2022. PMID: 36591537 Free PMC article.
Bacterial membrane vesicles as promising vaccine candidates.
Jiang L, Schinkel M, van Essen M, Schiffelers RM. Jiang L, et al. Eur J Pharm Biopharm. 2019 Dec;145:1-6. doi: 10.1016/j.ejpb.2019.09.021. Epub 2019 Sep 24. Eur J Pharm Biopharm. 2019. PMID: 31560955 Review.
Drug Delivery with Extracellular Vesicles: From Imagination to Innovation.
de Jong OG, Kooijmans SAA, Murphy DE, Jiang L, Evers MJW, Sluijter JPG, Vader P, Schiffelers RM. de Jong OG, et al. Among authors: jiang l. Acc Chem Res. 2019 Jul 16;52(7):1761-1770. doi: 10.1021/acs.accounts.9b00109. Epub 2019 Jun 5. Acc Chem Res. 2019. PMID: 31181910 Free PMC article.
MigraineTracker: Examining Patient Experiences with Goal-Directed Self-Tracking for a Chronic Health Condition.
Sefidgar YS, Castillo CL, Chopra S, Jiang L, Jones T, Mittal A, Ryu H, Schroeder J, Cole A, Murinova N, Munson SA, Fogarty J. Sefidgar YS, et al. Among authors: jiang l. Proc SIGCHI Conf Hum Factor Comput Syst. 2024 May;2024:129. doi: 10.1145/3613904.3642075. Epub 2024 May 11. Proc SIGCHI Conf Hum Factor Comput Syst. 2024. PMID: 38741616 Free PMC article.
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