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In utero and postnatal VX-770 administration rescues multiorgan disease in a ferret model of cystic fibrosis.
Sun X, Yi Y, Yan Z, Rosen BH, Liang B, Winter MC, Evans TIA, Rotti PG, Yang Y, Gray JS, Park SY, Zhou W, Zhang Y, Moll SR, Woody L, Tran DM, Jiang L, Vonk AM, Beekman JM, Negulescu P, Van Goor F, Fiorino DF, Gibson-Corley KN, Engelhardt JF. Sun X, et al. Among authors: jiang l. Sci Transl Med. 2019 Mar 27;11(485):eaau7531. doi: 10.1126/scitranslmed.aau7531. Sci Transl Med. 2019. PMID: 30918114 Free PMC article.
Mammalian IRE1α dynamically and functionally coalesces with stress granules.
Liu S, Zhang X, Yao X, Wang G, Huang S, Chen P, Tang M, Cai J, Wu Z, Zhang Y, Xu R, Liu K, He K, Wang Y, Jiang L, Wang QA, Rui L, Liu J, Liu Y. Liu S, et al. Among authors: jiang l. Nat Cell Biol. 2024 May 7. doi: 10.1038/s41556-024-01418-7. Online ahead of print. Nat Cell Biol. 2024. PMID: 38714852
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