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TIA1 regulates the generation and response to toxic tau oligomers.
Jiang L, Ash PEA, Maziuk BF, Ballance HI, Boudeau S, Abdullatif AA, Orlando M, Petrucelli L, Ikezu T, Wolozin B. Jiang L, et al. Acta Neuropathol. 2019 Feb;137(2):259-277. doi: 10.1007/s00401-018-1937-5. Epub 2018 Nov 21. Acta Neuropathol. 2019. PMID: 30465259 Free PMC article.
RNA binding proteins co-localize with small tau inclusions in tauopathy.
Maziuk BF, Apicco DJ, Cruz AL, Jiang L, Ash PEA, da Rocha EL, Zhang C, Yu WH, Leszyk J, Abisambra JF, Li H, Wolozin B. Maziuk BF, et al. Among authors: jiang l. Acta Neuropathol Commun. 2018 Aug 1;6(1):71. doi: 10.1186/s40478-018-0574-5. Acta Neuropathol Commun. 2018. PMID: 30068389 Free PMC article.
Dysregulation of RNA Splicing in Tauopathies.
Apicco DJ, Zhang C, Maziuk B, Jiang L, Ballance HI, Boudeau S, Ung C, Li H, Wolozin B. Apicco DJ, et al. Among authors: jiang l. Cell Rep. 2019 Dec 24;29(13):4377-4388.e4. doi: 10.1016/j.celrep.2019.11.093. Cell Rep. 2019. PMID: 31875547 Free PMC article.
TIA1 potentiates tau phase separation and promotes generation of toxic oligomeric tau.
Ash PEA, Lei S, Shattuck J, Boudeau S, Carlomagno Y, Medalla M, Mashimo BL, Socorro G, Al-Mohanna LFA, Jiang L, Öztürk MM, Knobel M, Ivanov P, Petrucelli L, Wegmann S, Kanaan NM, Wolozin B. Ash PEA, et al. Among authors: jiang l. Proc Natl Acad Sci U S A. 2021 Mar 2;118(9):e2014188118. doi: 10.1073/pnas.2014188118. Proc Natl Acad Sci U S A. 2021. PMID: 33619090 Free PMC article.
Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy.
Jiang L, Lin W, Zhang C, Ash PEA, Verma M, Kwan J, van Vliet E, Yang Z, Cruz AL, Boudeau S, Maziuk BF, Lei S, Song J, Alvarez VE, Hovde S, Abisambra JF, Kuo MH, Kanaan N, Murray ME, Crary JF, Zhao J, Cheng JX, Petrucelli L, Li H, Emili A, Wolozin B. Jiang L, et al. Mol Cell. 2021 Oct 21;81(20):4209-4227.e12. doi: 10.1016/j.molcel.2021.07.038. Epub 2021 Aug 27. Mol Cell. 2021. PMID: 34453888 Free PMC article.
Accumulation of m6A exhibits stronger correlation with MAPT than β-amyloid pathology in an APPNL-G-F /MAPTP301S mouse model of Alzheimer's disease.
Jiang L, Roberts R, Wong M, Zhang L, Webber CJ, Kilci A, Jenkins M, Sun G, Rashad S, Sun J, Dedon PC, Daley SA, Xia W, Ortiz AR, Dorrian L, Saito T, Saido TC, Wolozin B. Jiang L, et al. bioRxiv [Preprint]. 2023 Mar 28:2023.03.28.534515. doi: 10.1101/2023.03.28.534515. bioRxiv. 2023. PMID: 37034774 Free PMC article. Preprint.
Accumulation of m6A exhibits stronger correlation with MAPT than β-amyloid pathology in an APPNL-G-F /MAPTP301S mouse model of Alzheimer's disease.
Jiang L, Roberts R, Wong M, Zhang L, Webber CJ, Kilci A, Jenkins M, Sun J, Sun G, Rashad S, Dedon PC, Daley SA, Xia W, Ortiz AR, Dorrian L, Saito T, Saido TC, Wolozin B. Jiang L, et al. Res Sq [Preprint]. 2023 May 18:rs.3.rs-2745852. doi: 10.21203/rs.3.rs-2745852/v1. Res Sq. 2023. PMID: 37292629 Free PMC article. Preprint.
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