Jiang J - Search Results

1

The application of omics-based human liver platforms for investigating the mechanism of drug-induced hepatotoxicity in vitro.

Jiang J, Pieterman CD, Ertaylan G, Peeters RLM, de Kok TMCM. Jiang J, et al. Arch Toxicol. 2019 Nov;93(11):3067-3098. doi: 10.1007/s00204-019-02585-5. Epub 2019 Oct 5. Arch Toxicol. 2019. PMID: 31586243 Review.

2

Increased mitochondrial ROS formation by acetaminophen in human hepatic cells is associated with gene expression changes suggesting disruption of the mitochondrial electron transport chain.

Jiang J, Briedé JJ, Jennen DG, Van Summeren A, Saritas-Brauers K, Schaart G, Kleinjans JC, de Kok TM. Jiang J, et al. Toxicol Lett. 2015 Apr 16;234(2):139-50. doi: 10.1016/j.toxlet.2015.02.012. Epub 2015 Feb 19. Toxicol Lett. 2015. PMID: 25704631

3

Response to cytochrome P450-derived versus mitochondrial oxidant stress in acetaminophen hepatotoxicity.

Jiang J, Briedé JJ, Jennen DG, Kleinjans JC, de Kok TM. Jiang J, et al. Toxicol Lett. 2015 Jun 15;235(3):218-9. doi: 10.1016/j.toxlet.2015.04.003. Epub 2015 Apr 17. Toxicol Lett. 2015. PMID: 25895633 No abstract available.

4

Development of novel tools for the in vitro investigation of drug-induced liver injury.

Jiang J, Wolters JE, van Breda SG, Kleinjans JC, de Kok TM. Jiang J, et al. Expert Opin Drug Metab Toxicol. 2015;11(10):1523-37. doi: 10.1517/17425255.2015.1065814. Epub 2015 Jul 9. Expert Opin Drug Metab Toxicol. 2015. PMID: 26155718 Review.

5

Omics-based identification of the combined effects of idiosyncratic drugs and inflammatory cytokines on the development of drug-induced liver injury.

Jiang J, Mathijs K, Timmermans L, Claessen SM, Hecka A, Weusten J, Peters R, van Delft JH, Kleinjans JCS, Jennen DGJ, de Kok TM. Jiang J, et al. Toxicol Appl Pharmacol. 2017 Oct 1;332:100-108. doi: 10.1016/j.taap.2017.07.014. Epub 2017 Jul 18. Toxicol Appl Pharmacol. 2017. PMID: 28733206

6

The idiosyncratic drug-induced gene expression changes in HepG2 cells.

Jiang J, Mathijs K, Timmermans L, Claessen SM, Hecka A, Weusten J, Peters R, van Delft JH, Kleinjans JCS, Jennen DGJ, de Kok TM. Jiang J, et al. Data Brief. 2017 Jul 29;14:462-468. doi: 10.1016/j.dib.2017.07.074. eCollection 2017 Oct. Data Brief. 2017. PMID: 28831409 Free PMC article.

7

Human 3D multicellular microtissues: An upgraded model for the in vitro mechanistic investigation of inflammation-associated drug toxicity.

Jiang J, Messner S, Kelm JM, van Herwijnen M, Jennen DGJ, Kleinjans JC, de Kok TM. Jiang J, et al. Toxicol Lett. 2019 Sep 15;312:34-44. doi: 10.1016/j.toxlet.2019.05.004. Epub 2019 May 3. Toxicol Lett. 2019. PMID: 31059760 Free article.

8

Unraveling the mechanisms underlying drug-induced cholestatic liver injury: identifying key genes using machine learning techniques on human in vitro data sets.

Jiang J, van Ertvelde J, Ertaylan G, Peeters R, Jennen D, de Kok TM, Vinken M. Jiang J, et al. Arch Toxicol. 2023 Nov;97(11):2969-2981. doi: 10.1007/s00204-023-03583-4. Epub 2023 Aug 21. Arch Toxicol. 2023. PMID: 37603094 Free PMC article.

9

A quantitative weight-of-evidence method for confidence assessment of adverse outcome pathway networks: A case study on chemical-induced liver steatosis.

Verhoeven A, van Ertvelde J, Boeckmans J, Gatzios A, Jover R, Lindeman B, Lopez-Soop G, Rodrigues RM, Rapisarda A, Sanz-Serrano J, Stinckens M, Sepehri S, Teunis M, Vinken M, Jiang J, Vanhaecke T. Verhoeven A, et al. Among authors: jiang j. Toxicology. 2024 Apr 25;505:153814. doi: 10.1016/j.tox.2024.153814. Online ahead of print. Toxicology. 2024. PMID: 38677583

10

A cellular census of human lungs identifies novel cell states in health and in asthma.

Vieira Braga FA, Kar G, Berg M, Carpaij OA, Polanski K, Simon LM, Brouwer S, Gomes T, Hesse L, Jiang J, Fasouli ES, Efremova M, Vento-Tormo R, Talavera-López C, Jonker MR, Affleck K, Palit S, Strzelecka PM, Firth HV, Mahbubani KT, Cvejic A, Meyer KB, Saeb-Parsy K, Luinge M, Brandsma CA, Timens W, Angelidis I, Strunz M, Koppelman GH, van Oosterhout AJ, Schiller HB, Theis FJ, van den Berge M, Nawijn MC, Teichmann SA. Vieira Braga FA, et al. Among authors: jiang j. Nat Med. 2019 Jul;25(7):1153-1163. doi: 10.1038/s41591-019-0468-5. Epub 2019 Jun 17. Nat Med. 2019. PMID: 31209336

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