Jiang H - Search Results

1

ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy.

Shi Y, Yamada K, Liddelow SA, Smith ST, Zhao L, Luo W, Tsai RM, Spina S, Grinberg LT, Rojas JC, Gallardo G, Wang K, Roh J, Robinson G, Finn MB, Jiang H, Sullivan PM, Baufeld C, Wood MW, Sutphen C, McCue L, Xiong C, Del-Aguila JL, Morris JC, Cruchaga C; Alzheimer’s Disease Neuroimaging Initiative; Fagan AM, Miller BL, Boxer AL, Seeley WW, Butovsky O, Barres BA, Paul SM, Holtzman DM. Shi Y, et al. Among authors: jiang h. Nature. 2017 Sep 28;549(7673):523-527. doi: 10.1038/nature24016. Epub 2017 Sep 20. Nature. 2017. PMID: 28959956 Free PMC article.

2

ABCA1 is required for normal central nervous system ApoE levels and for lipidation of astrocyte-secreted apoE.

Wahrle SE, Jiang H, Parsadanian M, Legleiter J, Han X, Fryer JD, Kowalewski T, Holtzman DM. Wahrle SE, et al. Among authors: jiang h. J Biol Chem. 2004 Sep 24;279(39):40987-93. doi: 10.1074/jbc.M407963200. Epub 2004 Jul 21. J Biol Chem. 2004. PMID: 15269217 Free article.

3

Deletion of Abca1 increases Abeta deposition in the PDAPP transgenic mouse model of Alzheimer disease.

Wahrle SE, Jiang H, Parsadanian M, Hartman RE, Bales KR, Paul SM, Holtzman DM. Wahrle SE, et al. Among authors: jiang h. J Biol Chem. 2005 Dec 30;280(52):43236-42. doi: 10.1074/jbc.M508780200. Epub 2005 Oct 5. J Biol Chem. 2005. PMID: 16207708 Free article.

4

P-glycoprotein deficiency at the blood-brain barrier increases amyloid-beta deposition in an Alzheimer disease mouse model.

Cirrito JR, Deane R, Fagan AM, Spinner ML, Parsadanian M, Finn MB, Jiang H, Prior JL, Sagare A, Bales KR, Paul SM, Zlokovic BV, Piwnica-Worms D, Holtzman DM. Cirrito JR, et al. Among authors: jiang h. J Clin Invest. 2005 Nov;115(11):3285-90. doi: 10.1172/JCI25247. Epub 2005 Oct 20. J Clin Invest. 2005. PMID: 16239972 Free PMC article.

5

Apolipoprotein E levels in cerebrospinal fluid and the effects of ABCA1 polymorphisms.

Wahrle SE, Shah AR, Fagan AM, Smemo S, Kauwe JS, Grupe A, Hinrichs A, Mayo K, Jiang H, Thal LJ, Goate AM, Holtzman DM. Wahrle SE, et al. Among authors: jiang h. Mol Neurodegener. 2007 Apr 12;2:7. doi: 10.1186/1750-1326-2-7. Mol Neurodegener. 2007. PMID: 17430597 Free PMC article.

6

Overexpression of ABCA1 reduces amyloid deposition in the PDAPP mouse model of Alzheimer disease.

Wahrle SE, Jiang H, Parsadanian M, Kim J, Li A, Knoten A, Jain S, Hirsch-Reinshagen V, Wellington CL, Bales KR, Paul SM, Holtzman DM. Wahrle SE, et al. Among authors: jiang h. J Clin Invest. 2008 Feb;118(2):671-82. doi: 10.1172/JCI33622. J Clin Invest. 2008. PMID: 18202749 Free PMC article.

7

Overexpression of low-density lipoprotein receptor in the brain markedly inhibits amyloid deposition and increases extracellular A beta clearance.

Kim J, Castellano JM, Jiang H, Basak JM, Parsadanian M, Pham V, Mason SM, Paul SM, Holtzman DM. Kim J, et al. Among authors: jiang h. Neuron. 2009 Dec 10;64(5):632-44. doi: 10.1016/j.neuron.2009.11.013. Neuron. 2009. PMID: 20005821 Free PMC article.

8

Human apoE isoforms differentially regulate brain amyloid-β peptide clearance.

Castellano JM, Kim J, Stewart FR, Jiang H, DeMattos RB, Patterson BW, Fagan AM, Morris JC, Mawuenyega KG, Cruchaga C, Goate AM, Bales KR, Paul SM, Bateman RJ, Holtzman DM. Castellano JM, et al. Among authors: jiang h. Sci Transl Med. 2011 Jun 29;3(89):89ra57. doi: 10.1126/scitranslmed.3002156. Sci Transl Med. 2011. PMID: 21715678 Free PMC article.

9

In vivo microdialysis reveals age-dependent decrease of brain interstitial fluid tau levels in P301S human tau transgenic mice.

Yamada K, Cirrito JR, Stewart FR, Jiang H, Finn MB, Holmes BB, Binder LI, Mandelkow EM, Diamond MI, Lee VM, Holtzman DM. Yamada K, et al. Among authors: jiang h. J Neurosci. 2011 Sep 14;31(37):13110-7. doi: 10.1523/JNEUROSCI.2569-11.2011. J Neurosci. 2011. PMID: 21917794 Free PMC article.

10

Haploinsufficiency of human APOE reduces amyloid deposition in a mouse model of amyloid-β amyloidosis.

Kim J, Jiang H, Park S, Eltorai AE, Stewart FR, Yoon H, Basak JM, Finn MB, Holtzman DM. Kim J, et al. Among authors: jiang h. J Neurosci. 2011 Dec 7;31(49):18007-12. doi: 10.1523/JNEUROSCI.3773-11.2011. J Neurosci. 2011. PMID: 22159114 Free PMC article.

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