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Pain-causing stinging nettle toxins target TMEM233 to modulate NaV1.7 function.
Jami S, Deuis JR, Klasfauseweh T, Cheng X, Kurdyukov S, Chung F, Okorokov AL, Li S, Zhang J, Cristofori-Armstrong B, Israel MR, Ju RJ, Robinson SD, Zhao P, Ragnarsson L, Andersson Å, Tran P, Schendel V, McMahon KL, Tran HNT, Chin YK, Zhu Y, Liu J, Crawford T, Purushothamvasan S, Habib AM, Andersson DA, Rash LD, Wood JN, Zhao J, Stehbens SJ, Mobli M, Leffler A, Jiang D, Cox JJ, Waxman SG, Dib-Hajj SD, Neely GG, Durek T, Vetter I. Jami S, et al. Among authors: jiang d. Nat Commun. 2023 Apr 28;14(1):2442. doi: 10.1038/s41467-023-37963-2. Nat Commun. 2023. PMID: 37117223 Free PMC article.
Structural basis for gating pore current in periodic paralysis.
Jiang D, Gamal El-Din TM, Ing C, Lu P, Pomès R, Zheng N, Catterall WA. Jiang D, et al. Nature. 2018 May;557(7706):590-594. doi: 10.1038/s41586-018-0120-4. Epub 2018 May 16. Nature. 2018. PMID: 29769724 Free PMC article.
N-type fast inactivation of a eukaryotic voltage-gated sodium channel.
Zhang J, Shi Y, Fan J, Chen H, Xia Z, Huang B, Jiang J, Gong J, Huang Z, Jiang D. Zhang J, et al. Among authors: jiang d, jiang j. Nat Commun. 2022 May 17;13(1):2713. doi: 10.1038/s41467-022-30400-w. Nat Commun. 2022. PMID: 35581266 Free PMC article.
Structural Advances in Voltage-Gated Sodium Channels.
Jiang D, Zhang J, Xia Z. Jiang D, et al. Front Pharmacol. 2022 Jun 3;13:908867. doi: 10.3389/fphar.2022.908867. eCollection 2022. Front Pharmacol. 2022. PMID: 35721169 Free PMC article. Review.
Structural basis for NaV1.7 inhibition by pore blockers.
Zhang J, Shi Y, Huang Z, Li Y, Yang B, Gong J, Jiang D. Zhang J, et al. Among authors: jiang d. Nat Struct Mol Biol. 2022 Dec;29(12):1208-1216. doi: 10.1038/s41594-022-00860-1. Epub 2022 Nov 24. Nat Struct Mol Biol. 2022. PMID: 36424527
Structural mechanism of voltage-gated sodium channel slow inactivation.
Chen H, Xia Z, Dong J, Huang B, Zhang J, Zhou F, Yan R, Shi Y, Gong J, Jiang J, Huang Z, Jiang D. Chen H, et al. Among authors: jiang d, jiang j. Nat Commun. 2024 May 1;15(1):3691. doi: 10.1038/s41467-024-48125-3. Nat Commun. 2024. PMID: 38693179 Free PMC article.
Structural basis of human Slo2.2 channel gating and modulation.
Zhang J, Liu S, Fan J, Yan R, Huang B, Zhou F, Yuan T, Gong J, Huang Z, Jiang D. Zhang J, et al. Among authors: jiang d. Cell Rep. 2023 Aug 29;42(8):112858. doi: 10.1016/j.celrep.2023.112858. Epub 2023 Jul 25. Cell Rep. 2023. PMID: 37494189 Free article.
7,604 results