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SR9009 has REV-ERB-independent effects on cell proliferation and metabolism.
Dierickx P, Emmett MJ, Jiang C, Uehara K, Liu M, Adlanmerini M, Lazar MA. Dierickx P, et al. Among authors: jiang c. Proc Natl Acad Sci U S A. 2019 Jun 18;116(25):12147-12152. doi: 10.1073/pnas.1904226116. Epub 2019 May 24. Proc Natl Acad Sci U S A. 2019. PMID: 31127047 Free PMC article.
Circadian REV-ERBs repress E4bp4 to activate NAMPT-dependent NAD+ biosynthesis and sustain cardiac function.
Dierickx P, Zhu K, Carpenter BJ, Jiang C, Vermunt MW, Xiao Y, Luongo TS, Yamamoto T, Martí-Pàmies Í, Mia S, Latimer M, Diwan A, Zhao J, Hauck AK, Krusen B, Nguyen HCB, Blobel GA, Kelly DP, Pei L, Baur JA, Young ME, Lazar MA. Dierickx P, et al. Among authors: jiang c. Nat Cardiovasc Res. 2022 Jan;1(1):45-58. doi: 10.1038/s44161-021-00001-9. Epub 2021 Dec 23. Nat Cardiovasc Res. 2022. PMID: 35036997 Free PMC article.
Isoform-specific functions of PPARγ in gene regulation and metabolism.
Hu W, Jiang C, Kim M, Xiao Y, Richter HJ, Guan D, Zhu K, Krusen BM, Roberts AN, Miller J, Steger DJ, Lazar MA. Hu W, et al. Among authors: jiang c. Genes Dev. 2022 Mar 1;36(5-6):300-312. doi: 10.1101/gad.349232.121. Epub 2022 Mar 10. Genes Dev. 2022. PMID: 35273075 Free PMC article.
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