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The Interaction of DNA-Binding Ligands with Trinucleotide-Repeat DNA: Implications for Therapy and Diagnosis of Neurological Disorders.
Curr Top Med Chem. 2015;15(14):1398-408. doi: 10.2174/1568026615666150413155030.
Curr Top Med Chem. 2015.
PMID: 25866276
Review.
Structural basis for the identification of an i-motif tetraplex core with a parallel-duplex junction as a structural motif in CCG triplet repeats.
Chen YW, Jhan CR, Neidle S, Hou MH.
Chen YW, et al. Among authors: jhan cr.
Angew Chem Int Ed Engl. 2014 Sep 26;53(40):10682-6. doi: 10.1002/anie.201405637. Epub 2014 Aug 19.
Angew Chem Int Ed Engl. 2014.
PMID: 25139267
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CoII(Chromomycin)₂ Complex Induces a Conformational Change of CCG Repeats from i-Motif to Base-Extruded DNA Duplex.
Chen YW, Satange R, Wu PC, Jhan CR, Chang CK, Chung KR, Waring MJ, Lin SW, Hsieh LC, Hou MH.
Chen YW, et al. Among authors: jhan cr.
Int J Mol Sci. 2018 Sep 17;19(9):2796. doi: 10.3390/ijms19092796.
Int J Mol Sci. 2018.
PMID: 30227633
Free PMC article.
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Targeting the ALS/FTD-associated A-DNA kink with anthracene-based metal complex causes DNA backbone straightening and groove contraction.
Jhan CR, Satange R, Wang SC, Zeng JY, Horng YC, Jin P, Neidle S, Hou MH.
Jhan CR, et al.
Nucleic Acids Res. 2021 Sep 20;49(16):9526-9538. doi: 10.1093/nar/gkab227.
Nucleic Acids Res. 2021.
PMID: 33836081
Free PMC article.
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