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HDAC6 modulates myofibril stiffness and diastolic function of the heart.
Lin YH, Major JL, Liebner T, Hourani Z, Travers JG, Wennersten SA, Haefner KR, Cavasin MA, Wilson CE, Jeong MY, Han Y, Gotthardt M, Ferguson SK, Ambardekar AV, Lam MP, Choudhary C, Granzier HL, Woulfe KC, McKinsey TA. Lin YH, et al. Among authors: jeong my. J Clin Invest. 2022 May 16;132(10):e148333. doi: 10.1172/JCI148333. J Clin Invest. 2022. PMID: 35575093 Free PMC article.
Cardiac HDAC6 catalytic activity is induced in response to chronic hypertension.
Lemon DD, Horn TR, Cavasin MA, Jeong MY, Haubold KW, Long CS, Irwin DC, McCune SA, Chung E, Leinwand LA, McKinsey TA. Lemon DD, et al. Among authors: jeong my. J Mol Cell Cardiol. 2011 Jul;51(1):41-50. doi: 10.1016/j.yjmcc.2011.04.005. Epub 2011 Apr 23. J Mol Cell Cardiol. 2011. PMID: 21539845 Free PMC article.
HDAC6 contributes to pathological responses of heart and skeletal muscle to chronic angiotensin-II signaling.
Demos-Davies KM, Ferguson BS, Cavasin MA, Mahaffey JH, Williams SM, Spiltoir JI, Schuetze KB, Horn TR, Chen B, Ferrara C, Scellini B, Piroddi N, Tesi C, Poggesi C, Jeong MY, McKinsey TA. Demos-Davies KM, et al. Among authors: jeong my. Am J Physiol Heart Circ Physiol. 2014 Jul 15;307(2):H252-8. doi: 10.1152/ajpheart.00149.2014. Epub 2014 May 23. Am J Physiol Heart Circ Physiol. 2014. PMID: 24858848 Free PMC article.
Histone deacetylase activity governs diastolic dysfunction through a nongenomic mechanism.
Jeong MY, Lin YH, Wennersten SA, Demos-Davies KM, Cavasin MA, Mahaffey JH, Monzani V, Saripalli C, Mascagni P, Reece TB, Ambardekar AV, Granzier HL, Dinarello CA, McKinsey TA. Jeong MY, et al. Sci Transl Med. 2018 Feb 7;10(427):eaao0144. doi: 10.1126/scitranslmed.aao0144. Sci Transl Med. 2018. PMID: 29437146 Free PMC article.
HDAC inhibition improves cardiopulmonary function in a feline model of diastolic dysfunction.
Wallner M, Eaton DM, Berretta RM, Liesinger L, Schittmayer M, Gindlhuber J, Wu J, Jeong MY, Lin YH, Borghetti G, Baker ST, Zhao H, Pfleger J, Blass S, Rainer PP, von Lewinski D, Bugger H, Mohsin S, Graier WF, Zirlik A, McKinsey TA, Birner-Gruenberger R, Wolfson MR, Houser SR. Wallner M, et al. Among authors: jeong my. Sci Transl Med. 2020 Jan 8;12(525):eaay7205. doi: 10.1126/scitranslmed.aay7205. Sci Transl Med. 2020. PMID: 31915304 Free PMC article.
193 results