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The Vinca minor genome highlights conserved evolutionary traits in monoterpene indole alkaloid synthesis.
Stander EA, Cuello C, Birer-Williams C, Kulagina N, Jansen HJ, Carqueijeiro I, Méteignier LV, Vergès V, Oudin A, Papon N, Dirks RP, Jensen MK, O'Connor SE, Dugé de Bernonville T, Besseau S, Courdavault V. Stander EA, et al. Among authors: jensen mk. G3 (Bethesda). 2022 Dec 1;12(12):jkac268. doi: 10.1093/g3journal/jkac268. G3 (Bethesda). 2022. PMID: 36200869 Free PMC article.
A microbial supply chain for production of the anti-cancer drug vinblastine.
Zhang J, Hansen LG, Gudich O, Viehrig K, Lassen LMM, Schrübbers L, Adhikari KB, Rubaszka P, Carrasquer-Alvarez E, Chen L, D'Ambrosio V, Lehka B, Haidar AK, Nallapareddy S, Giannakou K, Laloux M, Arsovska D, Jørgensen MAK, Chan LJG, Kristensen M, Christensen HB, Sudarsan S, Stander EA, Baidoo E, Petzold CJ, Wulff T, O'Connor SE, Courdavault V, Jensen MK, Keasling JD. Zhang J, et al. Among authors: jensen mk. Nature. 2022 Sep;609(7926):341-347. doi: 10.1038/s41586-022-05157-3. Epub 2022 Aug 31. Nature. 2022. PMID: 36045295 Free PMC article.
Genome Assembly of the Medicinal Plant Voacanga thouarsii.
Cuello C, Stander EA, Jansen HJ, Dugé de Bernonville T, Lanoue A, Giglioli-Guivarc'h N, Papon N, Dirks RP, Jensen MK, O'Connor SE, Besseau S, Courdavault V. Cuello C, et al. Among authors: jensen mk. Genome Biol Evol. 2022 Nov 4;14(11):evac158. doi: 10.1093/gbe/evac158. Genome Biol Evol. 2022. PMID: 36300641 Free PMC article.
An updated version of the Madagascar periwinkle genome.
Cuello C, Stander EA, Jansen HJ, Dugé De Bernonville T, Oudin A, Birer Williams C, Lanoue A, Giglioli Guivarc'h N, Papon N, Dirks RP, Jensen MK, O'Connor SE, Besseau S, Courdavault V. Cuello C, et al. Among authors: jensen mk. F1000Res. 2022 Dec 21;11:1541. doi: 10.12688/f1000research.129212.1. eCollection 2022. F1000Res. 2022. PMID: 36761838 Free PMC article.
Biosynthesis of natural and halogenated plant monoterpene indole alkaloids in yeast.
Bradley SA, Lehka BJ, Hansson FG, Adhikari KB, Rago D, Rubaszka P, Haidar AK, Chen L, Hansen LG, Gudich O, Giannakou K, Lengger B, Gill RT, Nakamura Y, de Bernonville TD, Koudounas K, Romero-Suarez D, Ding L, Qiao Y, Frimurer TM, Petersen AA, Besseau S, Kumar S, Gautron N, Melin C, Marc J, Jeanneau R, O'Connor SE, Courdavault V, Keasling JD, Zhang J, Jensen MK. Bradley SA, et al. Among authors: jensen mk. Nat Chem Biol. 2023 Dec;19(12):1551-1560. doi: 10.1038/s41589-023-01430-2. Epub 2023 Nov 6. Nat Chem Biol. 2023. PMID: 37932529 Free PMC article.
The Rauvolfia tetraphylla genome suggests multiple distinct biosynthetic routes for yohimbane monoterpene indole alkaloids.
Stander EA, Lehka B, Carqueijeiro I, Cuello C, Hansson FG, Jansen HJ, Dugé De Bernonville T, Birer Williams C, Vergès V, Lezin E, Lorensen MDBB, Dang TT, Oudin A, Lanoue A, Durand M, Giglioli-Guivarc'h N, Janfelt C, Papon N, Dirks RP, O'connor SE, Jensen MK, Besseau S, Courdavault V. Stander EA, et al. Among authors: jensen mk. Commun Biol. 2023 Nov 24;6(1):1197. doi: 10.1038/s42003-023-05574-8. Commun Biol. 2023. PMID: 38001233 Free PMC article.
A chromosome-scale genome assembly of Rauvolfia tetraphylla facilitates identification of the complete ajmaline biosynthetic pathway.
Lezin E, Carqueijeiro I, Cuello C, Durand M, Jansen HJ, Vergès V, Birer Williams C, Oudin A, Dugé de Bernonville T, Petrignet J, Celton N, St-Pierre B, Papon N, Sun C, Dirks RP, O'Connor SE, Jensen MK, Besseau S, Courdavault V. Lezin E, et al. Among authors: jensen mk. Plant Commun. 2024 Apr 8;5(4):100784. doi: 10.1016/j.xplc.2023.100784. Epub 2023 Dec 28. Plant Commun. 2024. PMID: 38155576 Free PMC article. No abstract available.
The Madagascar palm genome provides new insights on the evolution of Apocynaceae specialized metabolism.
Cuello C, Jansen HJ, Abdallah C, Zamar Mbadinga DL, Birer Williams C, Durand M, Oudin A, Papon N, Giglioli-Guivarc'h N, Dirks RP, Jensen MK, O'Connor SE, Besseau S, Courdavault V. Cuello C, et al. Among authors: jensen mk. Heliyon. 2024 Mar 14;10(6):e28078. doi: 10.1016/j.heliyon.2024.e28078. eCollection 2024 Mar 30. Heliyon. 2024. PMID: 38533072 Free PMC article.
Yeast Platforms for Production and Screening of Bioactive Derivatives of Rauwolscine.
Bradley SA, Hansson FG, Lehka BJ, Rago D, Pinho P, Peng H, Adhikari KB, Haidar AK, Hansen LG, Volkova D, Holtz M, Muyo Abad S, Ma X, Koudounas K, Besseau S, Gautron N, Mélin C, Marc J, Birer Williams C, Courdavault V, Jensen ED, Keasling JD, Zhang J, Jensen MK. Bradley SA, et al. Among authors: jensen mk. ACS Synth Biol. 2024 Apr 18. doi: 10.1021/acssynbio.4c00039. Online ahead of print. ACS Synth Biol. 2024. PMID: 38635307
532 results