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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 3
2004 2
2005 7
2006 7
2007 7
2008 9
2009 15
2010 18
2011 11
2012 14
2013 14
2014 13
2015 9
2016 11
2017 16
2018 12
2019 14
2020 10
2021 13
2022 13
2023 10
2024 6

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218 results

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Page 1
Single cell tracing of Pomc neurons reveals recruitment of 'Ghost' subtypes with atypical identity in a mouse model of obesity.
Leon S, Simon V, Lee TH, Steuernagel L, Clark S, Biglari N, Lesté-Lasserre T, Dupuy N, Cannich A, Bellocchio L, Zizzari P, Allard C, Gonzales D, Le Feuvre Y, Lhuillier E, Brochard A, Nicolas JC, Teillon J, Nikolski M, Marsicano G, Fioramonti X, Brüning JC, Cota D, Quarta C. Leon S, et al. Among authors: bruning jc. Nat Commun. 2024 Apr 24;15(1):3443. doi: 10.1038/s41467-024-47877-2. Nat Commun. 2024. PMID: 38658557 Free PMC article.
Depletion of TBC1D4 improves the metabolic exercise response by overcoming genetically induced peripheral insulin resistance.
Springer C, Binsch C, Weide D, Toska L, Cremer AL, Backes H, Scheel AK, Espelage L, Kotzka J, Sill S, Kurowski A, Kim D, Karpinski S, Schnurr TM, Hansen T, Hartwig S, Lehr S, Cames S, Brüning J, Lienhard M, Herwig R, Börno S, Timmermann B, Al-Hasani H, Chadt A. Springer C, et al. Among authors: bruning j. Diabetes. 2024 Apr 12:db230463. doi: 10.2337/db23-0463. Online ahead of print. Diabetes. 2024. PMID: 38608276
Activation of GFRAL+ neurons induces hypothermia and glucoregulatory responses associated with nausea and torpor.
Engström Ruud L, Font-Gironès F, Zajdel J, Kern L, Teixidor-Deulofeu J, Mannerås-Holm L, Carreras A, Becattini B, Björefeldt A, Hanse E, Fenselau H, Solinas G, Brüning JC, Wunderlich TF, Bäckhed F, Ruud J. Engström Ruud L, et al. Among authors: bruning jc. Cell Rep. 2024 Apr 23;43(4):113960. doi: 10.1016/j.celrep.2024.113960. Epub 2024 Mar 19. Cell Rep. 2024. PMID: 38507407 Free article.
Reciprocal activity of AgRP and POMC neurons governs coordinated control of feeding and metabolism.
De Solis AJ, Del Río-Martín A, Radermacher J, Chen W, Steuernagel L, Bauder CA, Eggersmann FR, Morgan DA, Cremer AL, Sué M, Germer M, Kukat C, Vollmar S, Backes H, Rahmouni K, Kloppenburg P, Brüning JC. De Solis AJ, et al. Among authors: bruning jc. Nat Metab. 2024 Mar;6(3):473-493. doi: 10.1038/s42255-024-00987-z. Epub 2024 Feb 20. Nat Metab. 2024. PMID: 38378998 Free PMC article.
CerS6-dependent ceramide synthesis in hypothalamic neurons promotes ER/mitochondrial stress and impairs glucose homeostasis in obese mice.
Hammerschmidt P, Steculorum SM, Bandet CL, Del Río-Martín A, Steuernagel L, Kohlhaas V, Feldmann M, Varela L, Majcher A, Quatorze Correia M, Klar RFU, Bauder CA, Kaya E, Porniece M, Biglari N, Sieben A, Horvath TL, Hornemann T, Brodesser S, Brüning JC. Hammerschmidt P, et al. Among authors: bruning jc. Nat Commun. 2023 Nov 29;14(1):7824. doi: 10.1038/s41467-023-42595-7. Nat Commun. 2023. PMID: 38016943 Free PMC article.
Liraglutide restores impaired associative learning in individuals with obesity.
Hanssen R, Rigoux L, Kuzmanovic B, Iglesias S, Kretschmer AC, Schlamann M, Albus K, Edwin Thanarajah S, Sitnikow T, Melzer C, Cornely OA, Brüning JC, Tittgemeyer M. Hanssen R, et al. Among authors: bruning jc. Nat Metab. 2023 Aug;5(8):1352-1363. doi: 10.1038/s42255-023-00859-y. Epub 2023 Aug 17. Nat Metab. 2023. PMID: 37592007 Free PMC article. Clinical Trial.
Development of a genetically-encoded sensor for probing endogenous nociceptin opioid peptide release.
Zhou X, Stine C, Prada PO, Fusca D, Assoumou K, Dernic J, Bhat MA, Achanta AS, Johnson JC, Jadhav S, Bauder CA, Steuernagel L, Ravotto L, Benke D, Weber B, Stoeber M, Kloppenburg P, Brüning JC, Bruchas MR, Patriarchi T. Zhou X, et al. Among authors: bruning jc. bioRxiv [Preprint]. 2023 Jun 1:2023.05.26.542102. doi: 10.1101/2023.05.26.542102. bioRxiv. 2023. PMID: 37292957 Free PMC article. Preprint.
218 results