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Stem cell-derived systems in toxicology assessment.
Suter-Dick L, Alves PM, Blaauboer BJ, Bremm KD, Brito C, Coecke S, Flick B, Fowler P, Hescheler J, Ingelman-Sundberg M, Jennings P, Kelm JM, Manou I, Mistry P, Moretto A, Roth A, Stedman D, van de Water B, Beilmann M. Suter-Dick L, et al. Among authors: jennings p. Stem Cells Dev. 2015 Jun 1;24(11):1284-96. doi: 10.1089/scd.2014.0540. Epub 2015 Mar 31. Stem Cells Dev. 2015. PMID: 25675366 Review.
The assessment of repeated dose toxicity in vitro: a proposed approach. The report and recommendations of ECVAM workshop 56.
Prieto P, Baird AW, Blaauboer BJ, Castell Ripoll JV, Corvi R, Dekant W, Dietl P, Gennari A, Gribaldo L, Griffin JL, Hartung T, Heindel JJ, Hoet P, Jennings P, Marocchio L, Noraberg J, Pazos P, Westmoreland C, Wolf A, Wright J, Pfaller W. Prieto P, et al. Among authors: jennings p. Altern Lab Anim. 2006 Jun;34(3):315-41. doi: 10.1177/026119290603400307. Altern Lab Anim. 2006. PMID: 16831063 No abstract available.
Application of integrated transcriptomic, proteomic and metabolomic profiling for the delineation of mechanisms of drug induced cell stress.
Wilmes A, Limonciel A, Aschauer L, Moenks K, Bielow C, Leonard MO, Hamon J, Carpi D, Ruzek S, Handler A, Schmal O, Herrgen K, Bellwon P, Burek C, Truisi GL, Hewitt P, Di Consiglio E, Testai E, Blaauboer BJ, Guillou C, Huber CG, Lukas A, Pfaller W, Mueller SO, Bois FY, Dekant W, Jennings P. Wilmes A, et al. Among authors: jennings p. J Proteomics. 2013 Feb 21;79:180-94. doi: 10.1016/j.jprot.2012.11.022. Epub 2012 Dec 10. J Proteomics. 2013. PMID: 23238060 Free article.
"Watching the Detectives" report of the general assembly of the EU project DETECTIVE Brussels, 24-25 November 2015.
Fernando RN, Chaudhari U, Escher SE, Hengstler JG, Hescheler J, Jennings P, Keun HC, Kleinjans JCS, Kolde R, Kollipara L, Kopp-Schneider A, Limonciel A, Nemade H, Nguemo F, Peterson H, Prieto P, Rodrigues RM, Sachinidis A, Schäfer C, Sickmann A, Spitkovsky D, Stöber R, van Breda SGJ, van de Water B, Vivier M, Zahedi RP, Vinken M, Rogiers V. Fernando RN, et al. Among authors: jennings p. Arch Toxicol. 2016 Jun;90(6):1529-1539. doi: 10.1007/s00204-016-1719-6. Epub 2016 Apr 29. Arch Toxicol. 2016. PMID: 27129694 Free PMC article.
Ensuring the Quality of Stem Cell-Derived In Vitro Models for Toxicity Testing.
Stacey GN, Coecke S, Price AB, Healy L, Jennings P, Wilmes A, Pinset C, Ingelman-Sundberg M, Louisse J, Haupt S, Kidd D, Robitski A, Jahnke HG, Lemaitre G, Myatt G. Stacey GN, et al. Among authors: jennings p. Adv Exp Med Biol. 2016;856:259-297. doi: 10.1007/978-3-319-33826-2_11. Adv Exp Med Biol. 2016. PMID: 27671727 Review.
Towards optimisation of induced pluripotent cell culture: Extracellular acidification results in growth arrest of iPSC prior to nutrient exhaustion.
Wilmes A, Rauch C, Carta G, Kern G, Meier F, Posch W, Wilflingseder D, Armstrong L, Lako M, Beilmann M, Gstraunthaler G, Jennings P. Wilmes A, et al. Among authors: jennings p. Toxicol In Vitro. 2017 Dec;45(Pt 3):445-454. doi: 10.1016/j.tiv.2017.07.023. Epub 2017 Aug 15. Toxicol In Vitro. 2017. PMID: 28821352
Adverse outcome pathways: opportunities, limitations and open questions.
Leist M, Ghallab A, Graepel R, Marchan R, Hassan R, Bennekou SH, Limonciel A, Vinken M, Schildknecht S, Waldmann T, Danen E, van Ravenzwaay B, Kamp H, Gardner I, Godoy P, Bois FY, Braeuning A, Reif R, Oesch F, Drasdo D, Höhme S, Schwarz M, Hartung T, Braunbeck T, Beltman J, Vrieling H, Sanz F, Forsby A, Gadaleta D, Fisher C, Kelm J, Fluri D, Ecker G, Zdrazil B, Terron A, Jennings P, van der Burg B, Dooley S, Meijer AH, Willighagen E, Martens M, Evelo C, Mombelli E, Taboureau O, Mantovani A, Hardy B, Koch B, Escher S, van Thriel C, Cadenas C, Kroese D, van de Water B, Hengstler JG. Leist M, et al. Among authors: jennings p. Arch Toxicol. 2017 Nov;91(11):3477-3505. doi: 10.1007/s00204-017-2045-3. Epub 2017 Oct 19. Arch Toxicol. 2017. PMID: 29051992 Review.
Advanced Good Cell Culture Practice for human primary, stem cell-derived and organoid models as well as microphysiological systems.
Pamies D, Bal-Price A, Chesné C, Coecke S, Dinnyes A, Eskes C, Grillari R, Gstraunthaler G, Hartung T, Jennings P, Leist M, Martin U, Passier R, Schwamborn JC, Stacey GN, Ellinger-Ziegelbauer H, Daneshian M. Pamies D, et al. Among authors: jennings p. ALTEX. 2018;35(3):353-378. doi: 10.14573/altex.1710081. Epub 2018 Apr 13. ALTEX. 2018. PMID: 29697851 Free article.
Differentiation of human iPSCs into functional podocytes.
Rauch C, Feifel E, Kern G, Murphy C, Meier F, Parson W, Beilmann M, Jennings P, Gstraunthaler G, Wilmes A. Rauch C, et al. Among authors: jennings p. PLoS One. 2018 Sep 17;13(9):e0203869. doi: 10.1371/journal.pone.0203869. eCollection 2018. PLoS One. 2018. PMID: 30222766 Free PMC article.
773 results