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Curcumin abrogates bile-induced NF-κB activity and DNA damage in vitro and suppresses NF-κB activity whilst promoting apoptosis in vivo, suggesting chemopreventative potential in Barrett's oesophagus.
Rawat N, Alhamdani A, McAdam E, Cronin J, Eltahir Z, Lewis P, Griffiths P, Baxter JN, Jenkins GJ. Rawat N, et al. Among authors: jenkins gj. Clin Transl Oncol. 2012 Apr;14(4):302-11. doi: 10.1007/s12094-012-0799-x. Clin Transl Oncol. 2012. PMID: 22484638
Influence of DNA repair on nonlinear dose-responses for mutation.
Thomas AD, Jenkins GJ, Kaina B, Bodger OG, Tomaszowski KH, Lewis PD, Doak SH, Johnson GE. Thomas AD, et al. Among authors: jenkins gj. Toxicol Sci. 2013 Mar;132(1):87-95. doi: 10.1093/toxsci/kfs341. Epub 2013 Jan 3. Toxicol Sci. 2013. PMID: 23288051 Free PMC article.
179 results