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Targeting IL-6 trans-signalling: past, present and future prospects.
Rose-John S, Jenkins BJ, Garbers C, Moll JM, Scheller J. Rose-John S, et al. Among authors: jenkins bj. Nat Rev Immunol. 2023 Oct;23(10):666-681. doi: 10.1038/s41577-023-00856-y. Epub 2023 Apr 17. Nat Rev Immunol. 2023. PMID: 37069261 Free PMC article. Review.
IL6 Trans-signaling Promotes KRAS-Driven Lung Carcinogenesis.
Brooks GD, McLeod L, Alhayyani S, Miller A, Russell PA, Ferlin W, Rose-John S, Ruwanpura S, Jenkins BJ. Brooks GD, et al. Among authors: jenkins bj. Cancer Res. 2016 Feb 15;76(4):866-76. doi: 10.1158/0008-5472.CAN-15-2388. Epub 2016 Jan 7. Cancer Res. 2016. PMID: 26744530
Therapeutic Targeting of the IL-6 Trans-Signaling/Mechanistic Target of Rapamycin Complex 1 Axis in Pulmonary Emphysema.
Ruwanpura SM, McLeod L, Dousha LF, Seow HJ, Alhayyani S, Tate MD, Deswaerte V, Brooks GD, Bozinovski S, MacDonald M, Garbers C, King PT, Bardin PG, Vlahos R, Rose-John S, Anderson GP, Jenkins BJ. Ruwanpura SM, et al. Among authors: jenkins bj. Am J Respir Crit Care Med. 2016 Dec 15;194(12):1494-1505. doi: 10.1164/rccm.201512-2368OC. Am J Respir Crit Care Med. 2016. PMID: 27373892
ADAM17 selectively activates the IL-6 trans-signaling/ERK MAPK axis in KRAS-addicted lung cancer.
Saad MI, Alhayyani S, McLeod L, Yu L, Alanazi M, Deswaerte V, Tang K, Jarde T, Smith JA, Prodanovic Z, Tate MD, Balic JJ, Watkins DN, Cain JE, Bozinovski S, Algar E, Kohmoto T, Ebi H, Ferlin W, Garbers C, Ruwanpura S, Sagi I, Rose-John S, Jenkins BJ. Saad MI, et al. Among authors: jenkins bj. EMBO Mol Med. 2019 Apr;11(4):e9976. doi: 10.15252/emmm.201809976. EMBO Mol Med. 2019. PMID: 30833304 Free PMC article.
ADAM17: An Emerging Therapeutic Target for Lung Cancer.
Saad MI, Rose-John S, Jenkins BJ. Saad MI, et al. Among authors: jenkins bj. Cancers (Basel). 2019 Aug 21;11(9):1218. doi: 10.3390/cancers11091218. Cancers (Basel). 2019. PMID: 31438559 Free PMC article. Review.
180 results