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Hijacking DNA methyltransferase transition state analogues to produce chemical scaffolds for PRMT inhibitors.
Halby L, Marechal N, Pechalrieu D, Cura V, Franchini DM, Faux C, Alby F, Troffer-Charlier N, Kudithipudi S, Jeltsch A, Aouadi W, Decroly E, Guillemot JC, Page P, Ferroud C, Bonnefond L, Guianvarc'h D, Cavarelli J, Arimondo PB. Halby L, et al. Among authors: jeltsch a. Philos Trans R Soc Lond B Biol Sci. 2018 Jun 5;373(1748):20170072. doi: 10.1098/rstb.2017.0072. Philos Trans R Soc Lond B Biol Sci. 2018. PMID: 29685976 Free PMC article.
C5-DNA methyltransferase inhibitors: from screening to effects on zebrafish embryo development.
Ceccaldi A, Rajavelu A, Champion C, Rampon C, Jurkowska R, Jankevicius G, Sénamaud-Beaufort C, Ponger L, Gagey N, Ali HD, Tost J, Vriz S, Ros S, Dauzonne D, Jeltsch A, Guianvarc'h D, Arimondo PB. Ceccaldi A, et al. Among authors: jeltsch a. Chembiochem. 2011 Jun 14;12(9):1337-45. doi: 10.1002/cbic.201100130. Epub 2011 Jun 1. Chembiochem. 2011. PMID: 21633996
DNA methyltransferase assays.
Jurkowska RZ, Ceccaldi A, Zhang Y, Arimondo PB, Jeltsch A. Jurkowska RZ, et al. Among authors: jeltsch a. Methods Mol Biol. 2011;791:157-77. doi: 10.1007/978-1-61779-316-5_13. Methods Mol Biol. 2011. PMID: 21913079
Rapid synthesis of new DNMT inhibitors derivatives of procainamide.
Halby L, Champion C, Sénamaud-Beaufort C, Ajjan S, Drujon T, Rajavelu A, Ceccaldi A, Jurkowska R, Lequin O, Nelson WG, Guy A, Jeltsch A, Guianvarc'h D, Ferroud C, Arimondo PB. Halby L, et al. Among authors: jeltsch a. Chembiochem. 2012 Jan 2;13(1):157-65. doi: 10.1002/cbic.201100522. Epub 2011 Dec 14. Chembiochem. 2012. PMID: 22170584
298 results