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The ATG5-binding and coiled coil domains of ATG16L1 maintain autophagy and tissue homeostasis in mice independently of the WD domain required for LC3-associated phagocytosis.
Rai S, Arasteh M, Jefferson M, Pearson T, Wang Y, Zhang W, Bicsak B, Divekar D, Powell PP, Naumann R, Beraza N, Carding SR, Florey O, Mayer U, Wileman T. Rai S, et al. Among authors: jefferson m. Autophagy. 2019 Apr;15(4):599-612. doi: 10.1080/15548627.2018.1534507. Epub 2018 Nov 7. Autophagy. 2019. PMID: 30403914 Free PMC article.
Non-canonical autophagy functions of ATG16L1 in epithelial cells limit lethal infection by influenza A virus.
Wang Y, Sharma P, Jefferson M, Zhang W, Bone B, Kipar A, Bitto D, Coombes JL, Pearson T, Man A, Zhekova A, Bao Y, Tripp RA, Carding SR, Yamauchi Y, Mayer U, Powell PP, Stewart JP, Wileman T. Wang Y, et al. Among authors: jefferson m. EMBO J. 2021 Mar 15;40(6):e105543. doi: 10.15252/embj.2020105543. Epub 2021 Feb 15. EMBO J. 2021. PMID: 33586810 Free PMC article.
Integrative analysis of Paneth cell proteomic and transcriptomic data from intestinal organoids reveals functional processes dependent on autophagy.
Jones EJ, Matthews ZJ, Gul L, Sudhakar P, Treveil A, Divekar D, Buck J, Wrzesinski T, Jefferson M, Armstrong SD, Hall LJ, Watson AJM, Carding SR, Haerty W, Di Palma F, Mayer U, Powell PP, Hautefort I, Wileman T, Korcsmaros T. Jones EJ, et al. Among authors: jefferson m. Dis Model Mech. 2019 Mar 18;12(3):dmm037069. doi: 10.1242/dmm.037069. Dis Model Mech. 2019. PMID: 30814064 Free PMC article.
167 results