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Intracellular VHHs to monitor and modulate GPCR signaling.
Raynaud P, Gauthier C, Jugnarain V, Jean-Alphonse F, Reiter E, Bruneau G, Crépieux P. Raynaud P, et al. Among authors: jean alphonse f. Front Endocrinol (Lausanne). 2022 Nov 16;13:1048601. doi: 10.3389/fendo.2022.1048601. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36465650 Free PMC article. Review.
Editorial: Pharmacology of endocrine related GPCRs.
De Pascali F, Hanyaloglu A, Jean-Alphonse F, Potì F, Reiter E. De Pascali F, et al. Among authors: jean alphonse f. Front Endocrinol (Lausanne). 2024 Feb 15;15:1379108. doi: 10.3389/fendo.2024.1379108. eCollection 2024. Front Endocrinol (Lausanne). 2024. PMID: 38425756 Free PMC article. No abstract available.
An intracellular VHH targeting the Luteinizing Hormone receptor modulates G protein-dependent signaling and steroidogenesis.
Gauthier C, Raynaud P, Jean-Alphonse F, Vallet A, Vaugrente O, Jugnarain V, Boulo T, Gauthier C, Reiter E, Bruneau G, Crépieux P. Gauthier C, et al. Among authors: jean alphonse f. Mol Cell Endocrinol. 2024 Apr 15;589:112235. doi: 10.1016/j.mce.2024.112235. Online ahead of print. Mol Cell Endocrinol. 2024. PMID: 38621656 Free article.
Combined Multiplexed Phage Display, High-Throughput Sequencing, and Functional Assays as a Platform for Identifying Modulatory VHHs Targeting the FSHR.
Zehnaker A, Vallet A, Gourdon J, Sarti C, Jugnarain V, Haj Hassan M, Mathias L, Gauthier C, Raynaud P, Boulo T, Beauclair L, Bigot Y, Casarini L, Crépieux P, Poupon A, Piégu B, Jean-Alphonse F, Bruneau G, Reiter É. Zehnaker A, et al. Among authors: jean alphonse f. Int J Mol Sci. 2023 Nov 4;24(21):15961. doi: 10.3390/ijms242115961. Int J Mol Sci. 2023. PMID: 37958944 Free PMC article.
Spatial bias in cAMP generation determines biological responses to PTH type 1 receptor activation.
White AD, Peña KA, Clark LJ, Maria CS, Liu S, Jean-Alphonse FG, Lee JY, Lei S, Cheng Z, Tu CL, Fang F, Szeto N, Gardella TJ, Xiao K, Gellman SH, Bahar I, Sutkeviciute I, Chang W, Vilardaga JP. White AD, et al. Among authors: jean alphonse fg. Sci Signal. 2021 Oct 5;14(703):eabc5944. doi: 10.1126/scisignal.abc5944. Epub 2021 Oct 5. Sci Signal. 2021. PMID: 34609896 Free PMC article.
Pharmacological Characterization of Low Molecular Weight Biased Agonists at the Follicle Stimulating Hormone Receptor.
De Pascali F, Ayoub MA, Benevelli R, Sposini S, Lehoux J, Gallay N, Raynaud P, Landomiel F, Jean-Alphonse F, Gauthier C, Pellissier LP, Crépieux P, Poupon A, Inoue A, Joubert N, Viaud-Massuard MC, Casarini L, Simoni M, Hanyaloglu AC, Nataraja SG, Yu HN, Palmer SS, Yvinec R, Reiter E. De Pascali F, et al. Among authors: jean alphonse f. Int J Mol Sci. 2021 Sep 12;22(18):9850. doi: 10.3390/ijms22189850. Int J Mol Sci. 2021. PMID: 34576014 Free PMC article.
34 results