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LHRH-conjugated lytic peptides directly target prostate cancer cells.
Yates C, Sharp S, Jones J, Topps D, Coleman M, Aneja R, Jaynes J, Turner T. Yates C, et al. Among authors: jaynes j. Biochem Pharmacol. 2011 Jan 1;81(1):104-10. doi: 10.1016/j.bcp.2010.09.015. Epub 2010 Sep 30. Biochem Pharmacol. 2011. PMID: 20869347 Free PMC article.
An IP-10 (CXCL10)-derived peptide inhibits angiogenesis.
Yates-Binder CC, Rodgers M, Jaynes J, Wells A, Bodnar RJ, Turner T. Yates-Binder CC, et al. Among authors: jaynes j. PLoS One. 2012;7(7):e40812. doi: 10.1371/journal.pone.0040812. Epub 2012 Jul 16. PLoS One. 2012. PMID: 22815829 Free PMC article.
LC-MS/MS assay coupled with carboxylic acid magnetic bead affinity capture to quantitatively measure cationic host defense peptides (HDPs) in complex matrices with application to preclinical pharmacokinetic studies.
O'Neill MJ, Chan K, Jaynes JM, Knotts Z, Xu X, Abisoye-Ogunniyan A, Guerin T, Schlomer J, Li D, Cary JW, Rajasekaran K, Yates C, Kozlov S, Andresson T, Rudloff U. O'Neill MJ, et al. Among authors: jaynes jm. J Pharm Biomed Anal. 2020 Mar 20;181:113093. doi: 10.1016/j.jpba.2020.113093. Epub 2020 Jan 2. J Pharm Biomed Anal. 2020. PMID: 31931447 Free PMC article.
Mannose receptor (CD206) activation in tumor-associated macrophages enhances adaptive and innate antitumor immune responses.
Jaynes JM, Sable R, Ronzetti M, Bautista W, Knotts Z, Abisoye-Ogunniyan A, Li D, Calvo R, Dashnyam M, Singh A, Guerin T, White J, Ravichandran S, Kumar P, Talsania K, Chen V, Ghebremedhin A, Karanam B, Bin Salam A, Amin R, Odzorig T, Aiken T, Nguyen V, Bian Y, Zarif JC, de Groot AE, Mehta M, Fan L, Hu X, Simeonov A, Pate N, Abu-Asab M, Ferrer M, Southall N, Ock CY, Zhao Y, Lopez H, Kozlov S, de Val N, Yates CC, Baljinnyam B, Marugan J, Rudloff U. Jaynes JM, et al. Sci Transl Med. 2020 Feb 12;12(530):eaax6337. doi: 10.1126/scitranslmed.aax6337. Sci Transl Med. 2020. PMID: 32051227 Free PMC article.
A Novel CD206 Targeting Peptide Inhibits Bleomycin-Induced Pulmonary Fibrosis in Mice.
Ghebremedhin A, Salam AB, Adu-Addai B, Noonan S, Stratton R, Ahmed MSU, Khantwal C, Martin GR, Lin H, Andrews C, Karanam B, Rudloff U, Lopez H, Jaynes J, Yates C. Ghebremedhin A, et al. Among authors: jaynes j. Cells. 2023 Apr 26;12(9):1254. doi: 10.3390/cells12091254. Cells. 2023. PMID: 37174654 Free PMC article.
A Novel CD206 Targeting Peptide Inhibits Bleomycin Induced Pulmonary Fibrosis in Mice.
Ghebremedhin A, Salam AB, Adu-Addai B, Noonan S, Stratton R, Ahmed MSU, Khantwal C, Martin GR, Lin H, Andrews C, Karanam B, Rudloff U, Lopez H, Jaynes J, Yates C. Ghebremedhin A, et al. Among authors: jaynes j. bioRxiv [Preprint]. 2020 Jul 29:2020.07.27.218115. doi: 10.1101/2020.07.27.218115. bioRxiv. 2020. PMID: 32766584 Free PMC article. Updated. Preprint.
Designed Host Defense Peptides for the Treatment of Bacterial Keratitis.
Clemens LE, Jaynes J, Lim E, Kolar SS, Reins RY, Baidouri H, Hanlon S, McDermott AM, Woodburn KW. Clemens LE, et al. Among authors: jaynes j. Invest Ophthalmol Vis Sci. 2017 Dec 1;58(14):6273-6281. doi: 10.1167/iovs.17-22243. Invest Ophthalmol Vis Sci. 2017. PMID: 29242901 Free PMC article.
134 results