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Reducing Akt2 in retinal pigment epithelial cells causes a compensatory increase in Akt1 and attenuates diabetic retinopathy.
Liu H, Stepicheva NA, Ghosh S, Shang P, Chowdhury O, Daley RA, Yazdankhah M, Gupta U, Hose SL, Valapala M, Fitting CS, Strizhakova A, Shan Y, Feenstra D, Sahel JA, Jayagopal A, Handa JT, Zigler JS Jr, Fort PE, Sodhi A, Sinha D. Liu H, et al. Among authors: jayagopal a. Nat Commun. 2022 Oct 13;13(1):6045. doi: 10.1038/s41467-022-33773-0. Nat Commun. 2022. PMID: 36229454 Free PMC article.
βA1-crystallin regulates glucose metabolism and mitochondrial function in mouse retinal astrocytes by modulating PTP1B activity.
Ghosh S, Liu H, Yazdankhah M, Stepicheva N, Shang P, Vaidya T, Hose S, Gupta U, Calderon MJ, Hu MW, Nair AP, Weiss J, Fitting CS, Bhutto IA, Gadde SGK, Naik NK, Jaydev C, Lutty GA, Handa JT, Jayagopal A, Qian J, Sahel JA, Rajasundaram D, Sergeev Y, Zigler JS Jr, Sethu S, Watkins S, Ghosh A, Sinha D. Ghosh S, et al. Among authors: jayagopal a. Commun Biol. 2021 Feb 24;4(1):248. doi: 10.1038/s42003-021-01763-5. Commun Biol. 2021. PMID: 33627831 Free PMC article.
βA3/A1-crystallin regulates apical polarity and EGFR endocytosis in retinal pigmented epithelial cells.
Shang P, Stepicheva N, Teel K, McCauley A, Fitting CS, Hose S, Grebe R, Yazdankhah M, Ghosh S, Liu H, Strizhakova A, Weiss J, Bhutto IA, Lutty GA, Jayagopal A, Qian J, Sahel JA, Samuel Zigler J Jr, Handa JT, Sergeev Y, Rajala RVS, Watkins S, Sinha D. Shang P, et al. Among authors: jayagopal a. Commun Biol. 2021 Jul 8;4(1):850. doi: 10.1038/s42003-021-02386-6. Commun Biol. 2021. PMID: 34239035 Free PMC article.
Neutrophils homing into the retina trigger pathology in early age-related macular degeneration.
Ghosh S, Padmanabhan A, Vaidya T, Watson AM, Bhutto IA, Hose S, Shang P, Stepicheva N, Yazdankhah M, Weiss J, Das M, Gopikrishna S, Aishwarya, Yadav N, Berger T, Mak TW, Xia S, Qian J, Lutty GA, Jayagopal A, Zigler JS Jr, Sethu S, Handa JT, Watkins SC, Ghosh A, Sinha D. Ghosh S, et al. Among authors: jayagopal a. Commun Biol. 2019 Sep 20;2:348. doi: 10.1038/s42003-019-0588-y. eCollection 2019. Commun Biol. 2019. PMID: 31552301 Free PMC article.
BNIP3L-mediated mitophagy is required for mitochondrial remodeling during the differentiation of optic nerve oligodendrocytes.
Yazdankhah M, Ghosh S, Shang P, Stepicheva N, Hose S, Liu H, Chamling X, Tian S, Sullivan MLG, Calderon MJ, Fitting CS, Weiss J, Jayagopal A, Handa JT, Sahel JA, Zigler JS Jr, Kinchington PR, Zack DJ, Sinha D. Yazdankhah M, et al. Among authors: jayagopal a. Autophagy. 2021 Oct;17(10):3140-3159. doi: 10.1080/15548627.2020.1871204. Epub 2021 Jan 19. Autophagy. 2021. PMID: 33404293 Free PMC article.
Organ-On-A-Chip Technologies for Advanced Blood-Retinal Barrier Models.
Ragelle H, Goncalves A, Kustermann S, Antonetti DA, Jayagopal A. Ragelle H, et al. Among authors: jayagopal a. J Ocul Pharmacol Ther. 2020 Jan/Feb;36(1):30-41. doi: 10.1089/jop.2019.0017. Epub 2019 May 29. J Ocul Pharmacol Ther. 2020. PMID: 31140899 Free PMC article. Review.
Nanoengineering of therapeutics for retinal vascular disease.
Gahlaut N, Suarez S, Uddin MI, Gordon AY, Evans SM, Jayagopal A. Gahlaut N, et al. Among authors: jayagopal a. Eur J Pharm Biopharm. 2015 Sep;95(Pt B):323-30. doi: 10.1016/j.ejpb.2015.05.001. Epub 2015 May 28. Eur J Pharm Biopharm. 2015. PMID: 26022642 Free PMC article. Review.
40 results