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Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines.
Josa-Culleré L, Galan SRG, Cogswell TJ, Jackson TR, Jay-Smith M, Mola L, Greaves CR, Carter TS, Madden KS, Trott S, Zhang D, Bataille CJR, Davies SG, Vyas P, Milne TA, Naylor A, Wynne GM, Russell AJ. Josa-Culleré L, et al. Among authors: jay smith m. Eur J Med Chem. 2023 Oct 5;258:115509. doi: 10.1016/j.ejmech.2023.115509. Epub 2023 May 26. Eur J Med Chem. 2023. PMID: 37343464
Identification and Preliminary Structure-Activity Relationship Studies of 1,5-Dihydrobenzo[e][1,4]oxazepin-2(3H)-ones That Induce Differentiation of Acute Myeloid Leukemia Cells In Vitro.
Josa-Culleré L, Cogswell TJ, Georgiou I, Jay-Smith M, Jackson TR, Bataille CJR, Davies SG, Vyas P, Milne TA, Wynne GM, Russell AJ. Josa-Culleré L, et al. Among authors: jay smith m. Molecules. 2021 Nov 2;26(21):6648. doi: 10.3390/molecules26216648. Molecules. 2021. PMID: 34771052 Free PMC article.
Live applications of norbormide-based fluorescent probes in Drosophila melanogaster.
Forgiarini A, Wang Z, D'Amore C, Jay-Smith M, Li FF, Hopkins B, Brimble MA, Pagetta A, Bersani S, De Martin S, Napoli B, Bova S, Rennison D, Orso G. Forgiarini A, et al. Among authors: jay smith m. PLoS One. 2019 Apr 8;14(4):e0211169. doi: 10.1371/journal.pone.0211169. eCollection 2019. PLoS One. 2019. PMID: 30958824 Free PMC article.
Fatty Acid-Derived Pro-Toxicants of the Rat Selective Toxicant Norbormide.
Choi H, Conole D, Atkinson DJ, Laita O, Jay-Smith M, Pagano MA, Ribaudo G, Cavalli M, Bova S, Hopkins B, Brimble MA, Rennison D. Choi H, et al. Among authors: jay smith m. Chem Biodivers. 2016 Jun;13(6):762-75. doi: 10.1002/cbdv.201500241. Epub 2016 Jun 2. Chem Biodivers. 2016. PMID: 27144301