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Phenotypic screening identifies a trisubstituted imidazo[1,2-a]pyridine series that induces differentiation in multiple AML cell lines.
Eur J Med Chem. 2023 Oct 5;258:115509. doi: 10.1016/j.ejmech.2023.115509. Epub 2023 May 26.
Eur J Med Chem. 2023.
PMID: 37343464
Identification and Preliminary Structure-Activity Relationship Studies of 1,5-Dihydrobenzo[e][1,4]oxazepin-2(3H)-ones That Induce Differentiation of Acute Myeloid Leukemia Cells In Vitro.
Josa-Culleré L, Cogswell TJ, Georgiou I, Jay-Smith M, Jackson TR, Bataille CJR, Davies SG, Vyas P, Milne TA, Wynne GM, Russell AJ.
Josa-Culleré L, et al. Among authors: jay smith m.
Molecules. 2021 Nov 2;26(21):6648. doi: 10.3390/molecules26216648.
Molecules. 2021.
PMID: 34771052
Free PMC article.
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Live applications of norbormide-based fluorescent probes in Drosophila melanogaster.
Forgiarini A, Wang Z, D'Amore C, Jay-Smith M, Li FF, Hopkins B, Brimble MA, Pagetta A, Bersani S, De Martin S, Napoli B, Bova S, Rennison D, Orso G.
Forgiarini A, et al. Among authors: jay smith m.
PLoS One. 2019 Apr 8;14(4):e0211169. doi: 10.1371/journal.pone.0211169. eCollection 2019.
PLoS One. 2019.
PMID: 30958824
Free PMC article.
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Synthesis and Biological Characterization of a New Norbormide Derived Bodipy FL-Conjugated Fluorescent Probe for Cell Imaging.
D'Amore C, Orso G, Forgiarini A, Ceolotto G, Rennison D, Ribaudo G, Jay-Smith M, Hopkins B, Brimble MA, Bova S.
D'Amore C, et al. Among authors: jay smith m.
Front Pharmacol. 2018 Sep 25;9:1055. doi: 10.3389/fphar.2018.01055. eCollection 2018.
Front Pharmacol. 2018.
PMID: 30319407
Free PMC article.
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Fatty Acid-Derived Pro-Toxicants of the Rat Selective Toxicant Norbormide.
Choi H, Conole D, Atkinson DJ, Laita O, Jay-Smith M, Pagano MA, Ribaudo G, Cavalli M, Bova S, Hopkins B, Brimble MA, Rennison D.
Choi H, et al. Among authors: jay smith m.
Chem Biodivers. 2016 Jun;13(6):762-75. doi: 10.1002/cbdv.201500241. Epub 2016 Jun 2.
Chem Biodivers. 2016.
PMID: 27144301
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Synthesis and methemoglobinemia-inducing properties of benzocaine isosteres designed as humane rodenticides.
Conole D, Beck TM, Jay-Smith M, Tingle MD, Eason CT, Brimble MA, Rennison D.
Conole D, et al. Among authors: jay smith m.
Bioorg Med Chem. 2014 Apr 1;22(7):2220-35. doi: 10.1016/j.bmc.2014.02.013. Epub 2014 Feb 20.
Bioorg Med Chem. 2014.
PMID: 24602400
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Prodrugs of N-dicarboximide derivatives of the rat selective toxicant norbormide.
Rennison D, Laita O, Conole D, Jay-Smith M, Knauf J, Bova S, Cavalli M, Hopkins B, Linthicum DS, Brimble MA.
Rennison D, et al. Among authors: jay smith m.
Bioorg Med Chem. 2013 Sep 15;21(18):5886-99. doi: 10.1016/j.bmc.2013.06.071. Epub 2013 Jul 10.
Bioorg Med Chem. 2013.
PMID: 23920483
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