Jay CM - Search Results

1

In vivo safety and antitumor efficacy of bifunctional small hairpin RNAs specific for the human Stathmin 1 oncoprotein.

Phadke AP, Jay CM, Wang Z, Chen S, Liu S, Haddock C, Kumar P, Pappen BO, Rao DD, Templeton NS, Daniels EQ, Webb C, Monsma D, Scott S, Dylewski D, Frieboes HB, Brunicardi FC, Senzer N, Maples PB, Nemunaitis J, Tong AW. Phadke AP, et al. Among authors: jay cm. DNA Cell Biol. 2011 Sep;30(9):715-26. doi: 10.1089/dna.2011.1240. Epub 2011 May 25. DNA Cell Biol. 2011. PMID: 21612405

2

Preclinical Biodistribution and Safety Evaluation of a pbi-shRNA STMN1 Lipoplex after Subcutaneous Delivery.

Wang Z, Jay CM, Evans C, Kumar P, Phalon C, Rao DD, Senzer N, Nemunaitis J. Wang Z, et al. Among authors: jay cm. Toxicol Sci. 2017 Feb;155(2):400-408. doi: 10.1093/toxsci/kfw223. Epub 2016 Nov 4. Toxicol Sci. 2017. PMID: 27815492

3

Bifunctional short hairpin RNA (bi-shRNA): design and pathway to clinical application.

Rao DD, Senzer N, Wang Z, Kumar P, Jay CM, Nemunaitis J. Rao DD, et al. Among authors: jay cm. Methods Mol Biol. 2013;942:259-78. doi: 10.1007/978-1-62703-119-6_14. Methods Mol Biol. 2013. PMID: 23027056

4

Enhanced target gene knockdown by a bifunctional shRNA: a novel approach of RNA interference.

Rao DD, Maples PB, Senzer N, Kumar P, Wang Z, Pappen BO, Yu Y, Haddock C, Jay C, Phadke AP, Chen S, Kuhn J, Dylewski D, Scott S, Monsma D, Webb C, Tong A, Shanahan D, Nemunaitis J. Rao DD, et al. Cancer Gene Ther. 2010 Nov;17(11):780-91. doi: 10.1038/cgt.2010.35. Epub 2010 Jul 2. Cancer Gene Ther. 2010. PMID: 20596090

5

Preclinical Justification of pbi-shRNA EWS/FLI1 Lipoplex (LPX) Treatment for Ewing's Sarcoma.

Rao DD, Jay C, Wang Z, Luo X, Kumar P, Eysenbach H, Ghisoli M, Senzer N, Nemunaitis J. Rao DD, et al. Mol Ther. 2016 Aug;24(8):1412-22. doi: 10.1038/mt.2016.93. Epub 2016 May 11. Mol Ther. 2016. PMID: 27166877 Free PMC article.

6

Phase 1 Trial of Bi-shRNA STMN1 BIV in Refractory Cancer.

Barve M, Wang Z, Kumar P, Jay CM, Luo X, Bedell C, Mennel RG, Wallraven G, Brunicardi FC, Senzer N, Nemunaitis J, Rao DD. Barve M, et al. Among authors: jay cm. Mol Ther. 2015 Jun;23(6):1123-1130. doi: 10.1038/mt.2015.14. Epub 2015 Jan 26. Mol Ther. 2015. PMID: 25619726 Free PMC article. Clinical Trial.

7

KRAS mutant allele-specific expression knockdown in pancreatic cancer model with systemically delivered bi-shRNA KRAS lipoplex.

Rao DD, Luo X, Wang Z, Jay CM, Brunicardi FC, Maltese W, Manning L, Senzer N, Nemunaitis J. Rao DD, et al. Among authors: jay cm. PLoS One. 2018 May 31;13(5):e0193644. doi: 10.1371/journal.pone.0193644. eCollection 2018. PLoS One. 2018. PMID: 29851957 Free PMC article.

8

Assessment of intravenous pbi-shRNA PDX1 nanoparticle (OFHIRNA-PDX1) in yucatan swine.

Jay CM, Ruoff C, Kumar P, Maass H, Spanhel B, Miller M, Arrington A, Montalvo N, Gresham V, Rao DD, Evans C, Wang Z, Brunicardi FC, Liu SH, Zhou G, Senzer N, Nemunaitis J, King L, Weeks B, Clubb FJ, Fossum TW, Maples PB. Jay CM, et al. Cancer Gene Ther. 2013 Dec;20(12):683-9. doi: 10.1038/cgt.2013.68. Epub 2013 Nov 29. Cancer Gene Ther. 2013. PMID: 24287722

9

Vertically integrated translational studies of PDX1 as a therapeutic target for pancreatic cancer via a novel bifunctional RNAi platform.

Wu J, Liu S, Yu J, Zhou G, Rao D, Jay CM, Kumar P, Sanchez R, Templeton N, Senzer N, Maples P, Nemunaitis J, Brunicardi FC. Wu J, et al. Among authors: jay cm. Cancer Gene Ther. 2014 Feb;21(2):48-53. doi: 10.1038/cgt.2013.84. Epub 2014 Jan 24. Cancer Gene Ther. 2014. PMID: 24457987 Review.

10

Systemic therapeutic gene delivery for cancer: crafting Paris' arrow.

Tong AW, Jay CM, Senzer N, Maples PB, Nemunaitis J. Tong AW, et al. Among authors: jay cm. Curr Gene Ther. 2009 Feb;9(1):45-60. doi: 10.2174/156652309787354630. Curr Gene Ther. 2009. PMID: 19275571 Review.

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