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Replication stress signaling is a therapeutic target in myelodysplastic syndromes with splicing factor mutations.
Flach J, Jann JC, Knaflic A, Riabov V, Streuer A, Altrock E, Xu Q, Schmitt N, Obländer J, Nowak V, Danner J, Mehralivand A, Hofmann F, Palme I, Jawhar A, Wuchter P, Metzgeroth G, Nolte F, Hofmann WK, Nowak D. Flach J, et al. Among authors: jawhar a. Haematologica. 2021 Nov 1;106(11):2906-2917. doi: 10.3324/haematol.2020.254193. Haematologica. 2021. PMID: 33054116 Free PMC article.
High erythroferrone expression in CD71+ erythroid progenitors predicts superior survival in myelodysplastic syndromes.
Riabov V, Mossner M, Stöhr A, Jann JC, Streuer A, Schmitt N, Knaflic A, Nowak V, Weimer N, Obländer J, Palme I, Schumann C, Baldus CD, Schulze TJ, Wuchter P, Röhl H, Jawhar A, Weiss C, Boch T, Metzgeroth G, Neumann M, Hofmann WK, Nolte F, Nowak D. Riabov V, et al. Among authors: jawhar a. Br J Haematol. 2021 Mar;192(5):879-891. doi: 10.1111/bjh.17314. Epub 2021 Jan 24. Br J Haematol. 2021. PMID: 33486765
Preclinical evaluation of eltrombopag in a PDX model of myelodysplastic syndromes.
Schmitt N, Jann JC, Altrock E, Flach J, Danner J, Uhlig S, Streuer A, Knaflic A, Riabov V, Xu Q, Mehralivand A, Palme I, Nowak V, Obländer J, Weimer N, Haselmann V, Jawhar A, Darwich A, Weis CA, Marx A, Steiner L, Jawhar M, Metzgeroth G, Boch T, Nolte F, Hofmann WK, Nowak D. Schmitt N, et al. Among authors: jawhar m, jawhar a. Leukemia. 2022 Jan;36(1):236-247. doi: 10.1038/s41375-021-01327-w. Epub 2021 Jun 25. Leukemia. 2022. PMID: 34172896 Free PMC article.
40 results