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Page 1
Reverse TCR repertoire evolution toward dominant low-affinity clones during chronic CMV infection.
Schober K, Voit F, Grassmann S, Müller TR, Eggert J, Jarosch S, Weißbrich B, Hoffmann P, Borkner L, Nio E, Fanchi L, Clouser CR, Radhakrishnan A, Mihatsch L, Lückemeier P, Leube J, Dössinger G, Klein L, Neuenhahn M, Oduro JD, Cicin-Sain L, Buchholz VR, Busch DH. Schober K, et al. Among authors: jarosch s. Nat Immunol. 2020 Apr;21(4):434-441. doi: 10.1038/s41590-020-0628-2. Epub 2020 Mar 16. Nat Immunol. 2020. PMID: 32205883
Skin and gut imprinted helper T cell subsets exhibit distinct functional phenotypes in central nervous system autoimmunity.
Hiltensperger M, Beltrán E, Kant R, Tyystjärvi S, Lepennetier G, Domínguez Moreno H, Bauer IJ, Grassmann S, Jarosch S, Schober K, Buchholz VR, Kenet S, Gasperi C, Öllinger R, Rad R, Muschaweckh A, Sie C, Aly L, Knier B, Garg G, Afzali AM, Gerdes LA, Kümpfel T, Franzenburg S, Kawakami N, Hemmer B, Busch DH, Misgeld T, Dornmair K, Korn T. Hiltensperger M, et al. Among authors: jarosch s. Nat Immunol. 2021 Jul;22(7):880-892. doi: 10.1038/s41590-021-00948-8. Epub 2021 Jun 7. Nat Immunol. 2021. PMID: 34099917 Free PMC article.
Single-cell RNA sequencing reveals ex vivo signatures of SARS-CoV-2-reactive T cells through 'reverse phenotyping'.
Fischer DS, Ansari M, Wagner KI, Jarosch S, Huang Y, Mayr CH, Strunz M, Lang NJ, D'Ippolito E, Hammel M, Mateyka L, Weber S, Wolff LS, Witter K, Fernandez IE, Leuschner G, Milger K, Frankenberger M, Nowak L, Heinig-Menhard K, Koch I, Stoleriu MG, Hilgendorff A, Behr J, Pichlmair A, Schubert B, Theis FJ, Busch DH, Schiller HB, Schober K. Fischer DS, et al. Among authors: jarosch s. Nat Commun. 2021 Jul 26;12(1):4515. doi: 10.1038/s41467-021-24730-4. Nat Commun. 2021. PMID: 34312385 Free PMC article.
Fate mapping of single NK cells identifies a type 1 innate lymphoid-like lineage that bridges innate and adaptive recognition of viral infection.
Flommersfeld S, Böttcher JP, Ersching J, Flossdorf M, Meiser P, Pachmayr LO, Leube J, Hensel I, Jarosch S, Zhang Q, Chaudhry MZ, Andrae I, Schiemann M, Busch DH, Cicin-Sain L, Sun JC, Gasteiger G, Victora GD, Höfer T, Buchholz VR, Grassmann S. Flommersfeld S, et al. Among authors: jarosch s. Immunity. 2021 Oct 12;54(10):2288-2304.e7. doi: 10.1016/j.immuni.2021.08.002. Epub 2021 Aug 25. Immunity. 2021. PMID: 34437840 Free PMC article.
Targeted T cell receptor gene editing provides predictable T cell product function for immunotherapy.
Müller TR, Jarosch S, Hammel M, Leube J, Grassmann S, Bernard B, Effenberger M, Andrä I, Chaudhry MZ, Käuferle T, Malo A, Cicin-Sain L, Steinberger P, Feuchtinger T, Protzer U, Schumann K, Neuenhahn M, Schober K, Busch DH. Müller TR, et al. Among authors: jarosch s. Cell Rep Med. 2021 Aug 17;2(8):100374. doi: 10.1016/j.xcrm.2021.100374. eCollection 2021 Aug 17. Cell Rep Med. 2021. PMID: 34467251 Free PMC article.
Recruitment of highly cytotoxic CD8+ T cell receptors in mild SARS-CoV-2 infection.
Wagner KI, Mateyka LM, Jarosch S, Grass V, Weber S, Schober K, Hammel M, Burrell T, Kalali B, Poppert H, Beyer H, Schambeck S, Holdenrieder S, Strötges-Achatz A, Haselmann V, Neumaier M, Erber J, Priller A, Yazici S, Roggendorf H, Odendahl M, Tonn T, Dick A, Witter K, Mijočević H, Protzer U, Knolle PA, Pichlmair A, Crowell CS, Gerhard M, D'Ippolito E, Busch DH. Wagner KI, et al. Among authors: jarosch s. Cell Rep. 2022 Jan 11;38(2):110214. doi: 10.1016/j.celrep.2021.110214. Epub 2021 Dec 17. Cell Rep. 2022. PMID: 34968416 Free PMC article.
Signatures of recent activation identify a circulating T cell compartment containing tumor-specific antigen receptors with high avidity.
Purcarea A, Jarosch S, Barton J, Grassmann S, Pachmayr L, D'Ippolito E, Hammel M, Hochholzer A, Wagner KI, van den Berg JH, Buchholz VR, Haanen JBAG, Busch DH, Schober K. Purcarea A, et al. Among authors: jarosch s. Sci Immunol. 2022 Aug 12;7(74):eabm2077. doi: 10.1126/sciimmunol.abm2077. Epub 2022 Aug 12. Sci Immunol. 2022. PMID: 35960818
31 results