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Sirtuin functions and modulation: from chemistry to the clinic.
Carafa V, Rotili D, Forgione M, Cuomo F, Serretiello E, Hailu GS, Jarho E, Lahtela-Kakkonen M, Mai A, Altucci L. Carafa V, et al. Among authors: jarho e. Clin Epigenetics. 2016 May 25;8:61. doi: 10.1186/s13148-016-0224-3. eCollection 2016. Clin Epigenetics. 2016. PMID: 27226812 Free PMC article. Review.
Natural polyphenols as sirtuin 6 modulators.
Rahnasto-Rilla M, Tyni J, Huovinen M, Jarho E, Kulikowicz T, Ravichandran S, A Bohr V, Ferrucci L, Lahtela-Kakkonen M, Moaddel R. Rahnasto-Rilla M, et al. Among authors: jarho e. Sci Rep. 2018 Mar 7;8(1):4163. doi: 10.1038/s41598-018-22388-5. Sci Rep. 2018. PMID: 29515203 Free PMC article.
BET Inhibition Upregulates SIRT1 and Alleviates Inflammatory Responses.
Kokkola T, Suuronen T, Pesonen M, Filippakopoulos P, Salminen A, Jarho EM, Lahtela-Kakkonen M. Kokkola T, et al. Among authors: jarho em. Chembiochem. 2015 Sep 21;16(14):1997-2001. doi: 10.1002/cbic.201500272. Epub 2015 Aug 13. Chembiochem. 2015. PMID: 26212199 Free PMC article.
Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins.
Christodoulou MS, Sacchetti A, Ronchetti V, Caufin S, Silvani A, Lesma G, Fontana G, Minicone F, Riva B, Ventura M, Lahtela-Kakkonen M, Jarho E, Zuco V, Zunino F, Martinet N, Dapiaggi F, Pieraccini S, Sironi M, Dalla Via L, Gia OM, Passarella D. Christodoulou MS, et al. Among authors: jarho e. Bioorg Med Chem. 2013 Nov 15;21(22):6920-8. doi: 10.1016/j.bmc.2013.09.030. Epub 2013 Sep 19. Bioorg Med Chem. 2013. PMID: 24103429
Peptides and Pseudopeptides as SIRT6 Deacetylation Inhibitors.
Kokkonen P, Rahnasto-Rilla M, Kiviranta PH, Huhtiniemi T, Laitinen T, Poso A, Jarho E, Lahtela-Kakkonen M. Kokkonen P, et al. Among authors: jarho e. ACS Med Chem Lett. 2012 Oct 23;3(12):969-74. doi: 10.1021/ml300139n. eCollection 2012 Dec 13. ACS Med Chem Lett. 2012. PMID: 24900419 Free PMC article.
N-Acylethanolamines Bind to SIRT6.
Rahnasto-Rilla M, Kokkola T, Jarho E, Lahtela-Kakkonen M, Moaddel R. Rahnasto-Rilla M, et al. Among authors: jarho e. Chembiochem. 2016 Jan 1;17(1):77-81. doi: 10.1002/cbic.201500482. Epub 2015 Nov 26. Chembiochem. 2016. PMID: 26607666 Free PMC article.
30 results